Evidence map›Paper›PMID 29942982›Full record

ArticleJournal of materials science. Materials in medicine2018

Early morphological changes in tissues when replacing abdominal wall defects by bacterial nanocellulose in experimental trials.

Andrey N Zharikov, Vladimir G Lubyansky, Evgenia K Gladysheva, Ekaterina A Skiba, Vera V Budaeva, Elena N Semyonova, Andrey A Zharikov, Gennady V Sakovich

Abstract readEvaluation Study
PubMed Publisher
In one paragraph

Article in Journal of materials science. Materials in medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Andrey N ZharikovChair of Neymark Departmental Surgery and Hospital Surgery, Altai State Medical University, Barnaul, Altai Krai, 656038, Russia. zhar67@mail.ru.
Vladimir G LubyanskyChair of Neymark Departmental Surgery and Hospital Surgery, Altai State Medical University, Barnaul, Altai Krai, 656038, Russia.
Evgenia K GladyshevaBioconversion Laboratory, Institute for Problems of Chemical and Energetic Technologies, Siberian Branch of the Russian Academy of Sciences (IPCET SB RAS), Biysk, Altai Krai, 659322, Russia.
Ekaterina A SkibaBioconversion Laboratory, Institute for Problems of Chemical and Energetic Technologies, Siberian Branch of the Russian Academy of Sciences (IPCET SB RAS), Biysk, Altai Krai, 659322, Russia.
Vera V BudaevaBioconversion Laboratory, Institute for Problems of Chemical and Energetic Technologies, Siberian Branch of the Russian Academy of Sciences (IPCET SB RAS), Biysk, Altai Krai, 659322, Russia.
Elena N SemyonovaAnatomical Pathology Department, Altai Krai Clinical Hospital, Barnaul, Altai Krai, 656024, Russia.
Andrey A ZharikovChair of Neymark Departmental Surgery and Hospital Surgery, Altai State Medical University, Barnaul, Altai Krai, 656038, Russia.
Gennady V SakovichBioconversion Laboratory, Institute for Problems of Chemical and Energetic Technologies, Siberian Branch of the Russian Academy of Sciences (IPCET SB RAS), Biysk, Altai Krai, 659322, Russia.
Siberian Branch of the Russian Academy of Sciences · RUAltai State Medical University · RURegional Public Health Care Institution "City Hospital No. 5, Barnaul" · RU

Funding

Russian Science Foundation Project # 17-19-01054
6 · The paper itself

Abstract

Experimental trials were done on five dogs to explore if an anterior abdominal wall defect could be repaired using wet (99.9%), compact BNC membranes produced by the Мedusomyces gisevii Sa-12 symbiotic culture. The abdominal wall defect was simulated by middle-midline laparotomy, and a BNC membrane was then fixed to open aponeurotic edges with blanket suture (Prolene 4-0, Ethicon). A comparative study was also done to reinforce the aponeurotic defect with both the BNC membrane and polypropylene mesh (PPM) (Ultrapro, Ethicon). The materials were harvested at 14 and 60 days postoperative to visually evaluate their location in the abdominal tissues and evaluate the presence of BNC and PPM adhesions to the intestinal loops, followed by histologic examination of the tissue response to these prosthetics. The BNC exhibited good fixation to the anterior abdominal wall to form on the 14th day a capsule of loose fibrin around the BNC. Active reparative processes were observed at the BNC site at 60 days post-surgery to generate new, stable connective-tissue elements (macrophages, giant cells, fibroblasts, fibrin) and neocapillaries. Negligible intraperitoneal adhesions were detected between the BNC and the intestinal loops as compared to the case of PPM. There were no suppurative complications throughout the postsurgical period. We noticed on the 60

Indexed as

Biocompatible MaterialsCelluloseAbdominal WallAnimalsBacteriaDogsFibrinHernia, AbdominalMaterials TestingNanostructuresNeovascularization, PhysiologicPolypropylenesSurgical MeshTime FactorsBiocompatible MaterialsCelluloseFibrinPolypropylenes

Identifiers

PMID29942982
OpenAlexW2809784187

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.