Evidence map›Paper›PMID 29942812›Full record

ArticleBurns & trauma2018

A retrospective cohort study to compare post-injury admissions for infectious diseases in burn patients, non-burn trauma patients and uninjured people.

Janine M Duke, Sean M Randall, James H Boyd, Mark W Fear, Suzanne Rea, Fiona M Wood

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Burns & trauma, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Janine M Duke1Burn Injury Research Unit, Faculty Health and Medical Sciences, The University of Western Australia, Perth, WA Australia.ORCID 0000-0002-4724-4948
Sean M Randall2Centre for Data Linkage, Curtin University, Perth, WA Australia.
James H Boyd2Centre for Data Linkage, Curtin University, Perth, WA Australia.
Mark W Fear1Burn Injury Research Unit, Faculty Health and Medical Sciences, The University of Western Australia, Perth, WA Australia.
Suzanne Rea1Burn Injury Research Unit, Faculty Health and Medical Sciences, The University of Western Australia, Perth, WA Australia.
Fiona M Wood1Burn Injury Research Unit, Faculty Health and Medical Sciences, The University of Western Australia, Perth, WA Australia.
The University of Western Australia · AUCurtin University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInjury triggers a range of systemic effects including inflammation and immune responses. This study aimed to compare infectious disease admissions after burn and other types of injury using linked hospital admissions data.

methodsA retrospective longitudinal study using linked health data of all patients admitted with burns in Western Australia (

resultsAnnual age-standardised infectious disease admission rates were highest for the burn cohort, followed by the non-burn trauma and uninjured cohorts. Age-standardised admission rates by decade showed different patterns across major categories of infectious diseases, with the lower respiratory and skin and soft tissue infections the most common for those with burns and other open trauma. Compared with the uninjured, those with burns had twice the admission rate for infectious disease after discharge (incident rate ratio (IRR), 95% confidence interval (CI): 2.04, 1.98-2.11) while non-burn trauma experienced 1.74 times higher rates (95%CI: 1.68-1.81). The burn cohort experienced 10% higher rates of first-time admissions after discharge when compared with the non-burn trauma (hazard ratio (HR), 95%CI: 1.10, 1.05-1.15). Compared with the uninjured cohort, incident admissions were highest during the first 30 days after discharge for burns (HR, 95%CI: 5.18, 4.15-6.48) and non-burn trauma (HR, 95%CI: 5.06, 4.03-6.34). While incident rates remained high over the study period, the magnitude decreased with increasing time from discharge: burn vs uninjured: HR, 95%CI:

conclusionsBurns and non-burn trauma patients had higher admission rates for infectious diseases compared with age and gender matched uninjured people. The pattern of annual admission rates for major categories of infectious diseases varied across injury groups. Overall, the burn cohort experienced the highest rates for digestive, lower respiratory and skin and soft tissue infections. These results suggest long-term vulnerability to infectious disease after injury, possibly related to long-term immune dysfunction.

Indexed as

BurnCohortInfectious diseasesNo injuryNon-burn traumaPopulation-based

Identifiers

PMID29942812
PMCPMC5996559
OpenAlexW2807991531

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.