Evidence map›Paper›PMID 29942787›Full record

ArticleIDCases2018

Secondary immune thrombocytopenia (ITP) as an initial presentation of Whipple's disease.

David H Priest, Thomas H Grote, Sallie L Staley, William S Berger, Elizabeth S Norman, Brian S Smith

Open access · goldAbstract readCase Reports
In one paragraph

Article in IDCases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. A Family at War-AgainstOpen forum infectious diseases · 2025
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

David H PriestNovant Health Infectious Disease Specialists, 1381 Westgate Center Drive, Winston-Salem, NC 27103, USA.
Thomas H GroteNovant Health Oncology Specialists, 3333 Silas Creek Parkway, Winston-Salem, NC 27103, USA.
Sallie L StaleyNovant Health Oncology Specialists, 3333 Silas Creek Parkway, Winston-Salem, NC 27103, USA.
William S BergerNovant Health Salem Surgical Associates, 2915 Lyndhurst Avenue, Winston-Salem, NC 27103, USA.
Elizabeth S NormanPathologists Diagnostic Services, 3333 Silas Creek Parkway, Winston-Salem, NC 27103, USA.
Brian S SmithGastroenterology Associates of the Piedmont, 1901 South Hawthorne Road #310, Winston-Salem, NC 27103, USA.
Novant Health · USOncology Specialists · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immune thrombocytopenia (ITP) is a heterogeneous autoimmune disease characterized by low platelet count that has been associated with a number of chronic infections but rarely described as a manifestation of Whipple's disease (WD). We present a case of Whipple's disease in a patient initially diagnosed with ITP. A 46-year old male in the fifth decade of life presented with presumed idiopathic ITP and was treated with several therapies including corticosteroids, rituximab, and thrombopoietin receptor agonists. Several years later, he developed weight loss and worsening arthralgias. He was found to have evidence of WD in a jejunal lymph node, the duodenum, and the cerebral spinal fluid (CSF). His diagnosis of WD, as a cause of secondary ITP, came a full 8 years after he was discovered to have thrombocytopenia and over 4 years after he was diagnosed with ITP. WD is an uncommon, multiorgan system disease caused by the actinomycete

Indexed as

ITPThrombocytopeniaWhipple’s

Identifiers

PMID29942787
PMCPMC6010930
OpenAlexW2728207712

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.