Evidence map›Paper›PMID 29942715›Full record

ArticlePeerJ2018

Psychological, pharmacological, and combined treatments for binge eating disorder: a systematic review and meta-analysis.

Ata Ghaderi, Jenny Odeberg, Sanna Gustafsson, Maria Råstam, Agneta Brolund, Agneta Pettersson, Thomas Parling

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PeerJ, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 6 pooled it
9.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 6 syntheses or guidelines pooled it, 79 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Trial
  8. Trial
  9. Trial
  10. Review
  11. Review
  12. Bulimia Nervosa and Binge-Eating Disorder Across the Lifespan.Focus (American Psychiatric Publishing) · 2024
    Review
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Canadian family physician Medecin de famille canadien · 2022
    Review
  20. Canadian family physician Medecin de famille canadien · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Ata GhaderiDivision of Psychology, Department of Clinical Neuroscience, Karolinska Institute, Sweden.
Jenny OdebergSwedish Agency for Health Technology Assessment, and Assessment of Social Services, Stockholm, Sweden.
Sanna GustafssonUniversity Health Care Research Centre, Faculty of Medical Sciences, University College of Örebro, Örebro, Sweden.
Maria RåstamDepartment of Clinical Sciences, Lund University, Lund, Sweden.ORCID 0000-0003-0819-3946
Agneta BrolundSwedish Agency for Health Technology Assessment, and Assessment of Social Services, Stockholm, Sweden.
Agneta PetterssonSwedish Agency for Health Technology Assessment, and Assessment of Social Services, Stockholm, Sweden.
Thomas ParlingCentre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden.ORCID 0000-0002-6159-598X
SBU - Swedish Agency for Health Technology Assessment and Assessment of Social Services · SEKarolinska Institutet · SELund University · SEÖrebro University · SEStockholm County Council · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo systematically review the efficacy of psychological, pharmacological, and combined treatments for binge eating disorder (BED).

methodSystematic search and meta-analysis.

resultsWe found 45 unique studies with low/medium risk of bias, and moderate support for the efficacy of cognitive behavior therapy (CBT) and CBT guided self-help (with moderate quality of evidence), and modest support for interpersonal psychotherapy (IPT), selective serotonin reuptake inhibitors (SSRI), and lisdexamfetamine (with low quality of evidence) in the treatment of adults with BED in terms of cessation of or reduction in the frequency of binge eating. The results on weight loss were disappointing. Only lisdexamfetamine showed a very modest effect on weight loss (low quality of evidence). While there is limited support for the long-term effect of psychological treatments, we have currently no data to ascertain the long-term effect of drug treatments. Some undesired side effects are more common in drug treatment compared to placebo, while the side effects of psychological treatments are unknown. Direct comparisons between pharmaceutical and psychological treatments are lacking as well as data to generalize these results to adolescents.

conclusionWe found moderate support for the efficacy of CBT and guided self-help for the treatment of BED. However, IPT, SSRI, and lisdexamfetamine received only modest support in terms of cessation of or reduction in the frequency of binge eating. The lack of long-term follow-ups is alarming, especially with regard to medication. Long-term follow-ups, standardized assessments including measures of quality of life, and the study of underrepresented populations should be a priority for future research.

Indexed as

Binge eating disorderEating disorderLisdexamfetamineMeta-analysisPsychotherapySSRI

Identifiers

PMID29942715
PMCPMC6015752
OpenAlexW2808770184

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.