ArticleEvolution, medicine, and public health2018
Increasing variability of body mass and health correlates in Swiss conscripts, a possible role of relaxed natural selection?
Article in Evolution, medicine, and public health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Medical progress, relaxed natural selection, and adolescent obesity: implications for global health.Future science OA · 2026Article
- Article
- Evolutionary and anthropological perspectives on the sella turcica: from vertebrate origins to neurosurgical relevance.Journal of endocrinological investigation · 2026Review
- Total Meat Intake is Associated with Life Expectancy: A Cross-Sectional Data Analysis of 175 Contemporary Populations.International journal of general medicine · 2022Article
- Clash of the pandemics - At least 150'000 adults in Switzerland suffer from obesity grades 2 or 3 and are thus at elevated risk for severe COVID-19.F1000Research · 2020Article
- Residential Altitude Associates With Endurance but Not Muscle Power in Young Swiss Men.Frontiers in physiology · 2020Article
- Low fertility may be a significant determinant of ovarian cancer worldwide: an ecological analysis of cross- sectional data from 182 countries.Journal of ovarian research · 2018Article
- Article
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8 authors.
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Abstract
BACKGROUND AND
objectivesThe body mass index (BMI) is an established anthropometric index for the development of obesity-related conditions. However, little is known about the distribution of BMI within a population, especially about this distribution's temporal change. Here, we analysed changes in the distribution of height, weight and BMI over the past 140 years based on data of Swiss conscripts and tested for correlations between anthropometric data and standard blood parameters.
methodsHeight and weight were measured in 59 504 young Swiss males aged 18-19 years during conscription in 1875-79, 1932-36, 1994 and 2010-12. For 65% of conscripts in 2010-12, results of standard blood analysis were available. We calculated descriptive statistics of the distribution of height, weight and BMI over the four time periods and tested for associations between BMI and metabolic parameters.
resultsAverage and median body height, body weight and BMI increased over time. Height did no longer increase between 1994 and 2010-12, while weight and BMI still increased over these two decades. Variability ranges of weight and BMI increased over time, while variation of body height remained constant. Elevated levels of metabolic and inflammatory blood parameters were found at both ends of BMI distribution. CONCLUSIONS AND IMPLICATIONS: Both overweight and underweight subgroups showed similar changes in inflammation parameters, pointing toward related metabolic deficiencies in both conditions. In addition to environmental influences, our results indicate a potential role of relaxed natural selection on genes affecting metabolism and body composition.
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