ArticleClinical kidney journal2018
Clinical profile and outcome of pigment-induced nephropathy.
Article in Clinical kidney journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed, 54 citations in OpenAlex.
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- Rifampin-induced Acute Kidney Injury Is Associated With Hemolysis and Drug Re-exposure.Kidney medicine · 2026Article
- Unexpected acute kidney injury requiring dialysis after routine pulsed field pulmonary vein isolation: a case report.European heart journal. Case reports · 2026Article
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- Hemolytic Anemia Linked to Epstein-Barr Virus Infectious Mononucleosis: A Systematic Review of the Literature.Journal of clinical medicine · 2025Review
- A Series of Eight Cases of Pigment Nephropathy: An Obscured Aspect of Acute Kidney Injury.Cureus · 2024Article
- The kidney histopathological spectrum of patients with kidney injury following snakebite envenomation in India: scoping review of five decades.BMC nephrology · 2024Article
- Impella Versus Intra-Aortic Balloon Pump in Patients With Cardiogenic Shock Treated With Venoarterial Extracorporeal Membrane Oxygenation: An Observational Study.Journal of the American Heart Association · 2024Observational
- Clinical outcomes of rhabdomyolysis & validation of McMahon Score for risk prediction.The Indian journal of medical research · 2024Article
- Interesting Histology in Tropical Acute Kidney Injury.Kidney international reports · 2023Article
- Wasp venom-induced acute kidney injury: current progress and prospects.Renal failure · 2023Review
- A RARE CAUSE OF RECURRENT HAEMOLYTIC ANAEMIA: CARBOPLATIN AND PACLITAXEL-INDUCED AUTOIMMUNE HAEMOLYTIC ANAEMIA.European journal of case reports in internal medicine · 2023Article
- Predialysis serum lactate levels could predict dialysis withdrawal in Type 1 cardiorenal syndrome patients.EClinicalMedicine · 2022Article
- Association of Statins and 28-Day Mortality Rates in Patients Hospitalized With Severe Acute Respiratory Syndrome Coronavirus 2 Infection.The Journal of infectious diseases · 2022Article
- Macroscopic hematuria in wasp sting patients: a retrospective study.Renal failure · 2021Article
- Article
- Statins Are Associated with Improved 28-day Mortality in Patients Hospitalized with SARS-CoV-2 Infection.medRxiv : the preprint server for health sciences · 2021Article
- What does acute kidney injury and dark red-brown urine that appear after bone marrow transplantation tell us: Answers.Pediatric nephrology (Berlin, Germany) · 2021Article
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPigment nephropathy represents one of the most severe complications of rhabdomyolysis or hemolysis.
methodsWe performed a retrospective observational study to analyze the etiology, clinical manifestation, laboratory profile and outcome in patients with biopsy-proven pigment-induced nephropathy between January 2011 and December 2016. History, clinical examination findings, laboratory investigations and outcome were recorded.
resultsA total of 46 patients were included with mean follow-up of 14 ± 5.5 months. Mean age was 40.15 ± 12.3 years, 65% were males (male:female, 1.8:1) and ∼37 (80.4%) had oliguria. Mean serum creatinine at presentation and peak creatinine were 7.5 ± 2.2 and 12.1 ± 4.3 mg/dL, respectively. Evidence of rhabdomyolysis was noted in 26 patients (64%) and hemolysis in 20 patients (36%). Etiology of rhabdomyolysis include snake envenomation (10 patients), seizures (7), strenuous exercise (5), wasp sting (2) and rifampicin induced (2). The causes of hemolysis include rifampicin induced (7 patients), sepsis (5), malaria (3), mismatched blood transfusion/transfusion reaction (3) and paroxysmal nocturnal hemoglobinuria (2). On renal biopsy, two patients had acute interstitial nephritis and two had immunoglobulin A deposits in addition to pigment nephropathy. All except one (97.8%) required hemodialysis (HD) during hospital stay and mean number of HD sessions was 9 ± 2. A total of three patients with sepsis/disseminated intravascular coagulation died, all had associated hemolysis. On statistical analysis, there was no difference between AKI due to rhabdomyolysis and hemolysis except for high creatine phosphokinase in patients with rhabdomyolysis and Lactate dehydrogenase level in patients with hemolysis. At mean follow-up, five patients (12%) progressed to chronic kidney disease (CKD).
conclusionsPigment nephropathy due to rhabdomyolysis and hemolysis is an important cause of renal failure requiring HD. The prognosis was relatively good and depends on the etiology; however, long-term studies and follow-up are needed to assess the true incidence of CKD due to pigment nephropathy.
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