Evidence map›Paper›PMID 29942447›Full record

ArticleIranian journal of basic medical sciences2018

Selenium supplementation in the form of selenium nanoparticles and selenite sodium improves mature male mice reproductive performances.

Siamak Asri-Rezaei, Alireza Nourian, Ali Shalizar-Jalali, Gholamreza Najafi, Ali Nazarizadeh, Mobin Koohestani, Ali Karimi

Open access · greenAbstract read
In one paragraph

Article in Iranian journal of basic medical sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 43 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Trace elements and metal nanoparticles: mechanistic approaches to mitigating chemotherapy-induced toxicity-a review of literature evidence.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2024
    Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. Selenium nanoparticles derived fromRegenerative biomaterials · 2022
    Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Siamak Asri-RezaeiDepartment of Clinical Pathology and Internal Medicine, Faculty of Veterinary Medicine, Urmia University, Urmia, West Azerbaijan, Iran.
Alireza NourianDepartment of Basic Sciences, Faculty of Veterinary Medicine, Urmia University, Urmia, West Azerbaijan, Iran.
Ali Shalizar-JalaliDepartment of Basic Sciences, Faculty of Veterinary Medicine, Urmia University, Urmia, West Azerbaijan, Iran.
Gholamreza NajafiDepartment of Basic Sciences, Faculty of Veterinary Medicine, Urmia University, Urmia, West Azerbaijan, Iran.
Ali NazarizadehDepartment of Clinical Pathology and Internal Medicine, Faculty of Veterinary Medicine, Urmia University, Urmia, West Azerbaijan, Iran.
Mobin KoohestaniDepartment of Basic Sciences, Faculty of Veterinary Medicine, Urmia University, Urmia, West Azerbaijan, Iran.
Ali KarimiPh.D. Student of Histology, Faculty of Veterinary Medicine, Urmia University, Urmia, West Azerbaijan, Iran.
Urmia University of Technology · IRUrmia University · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe current study was conducted to examine the possible protective and retentive effects of one-week intra-peritoneal (IP) administration of selenium nanoparticles (Se-NPs), compared to its bulk counterpart, selenite sodium (Ss), after one complete cycle of spermatogenesis in mature male mice. MATERIALS AND

methodsThirty adult male mice were divided into 3 groups. Control group was administrated phosphate-buffered saline (IP) and the other groups received Ss (0.50 mg kg-1) and Se-NPs (0.50 mg kg-1) for seven successive days. Then, the animals were monitored for 28 days and finally sacrificed and tissue and blood samples were taken. Histopathological features, sperm quality, in vitro fertilization (IVF) capability and selenium (Se) content in testicular tissue were analyzed. Antioxidant enzyme activities including catalase, glutathione peroxidase, and superoxide dismutase as well as total antioxidant capacity and malondialdehyde levels were assessed in blood and the tissue samples.

resultsRemarkable differences were found in sperm characteristics, histopathological features and oxidative stress biomarkers between control and treatment groups. Moreover, IVF evaluation and tissue Se concentration examination weren't similar for Se-NPs and Ss.

conclusionConclusively, Se-treated groups had more antioxidant capacity than the control group, but sperm quality and histopathological features revealed that Se-NPs might possess more antioxidative and retentive potential compared to Ss in one spermatogenesis cycle.

Indexed as

MiceNanoparticleSeleniumSpermatogenesisTestis

Identifiers

PMID29942447
PMCPMC6015244
OpenAlexW2799282690

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.