Evidence map›Paper›PMID 29942387›Full record

ArticleNanobiomedicine

Microbubble-liposome conjugate: Payload evaluation of potential theranostic vehicle.

Ritu Malik, Ketan Pancholi, Andreas Melzer

Open access · hybridAbstract read
In one paragraph

Article in Nanobiomedicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.3field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Nested Nanobubbles for Ultrasound-Triggered Drug Release.ACS applied materials & interfaces · 2020
    Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Ritu MalikInstitute of Medical Sciences and Technology, University of Dundee, Dundee, UK.
Ketan PancholiSchool of Mechanical and Systems Engineering, Newcastle University, Newcastle upon Tyne, UK.
Andreas MelzerInstitute of Medical Sciences and Technology, University of Dundee, Dundee, UK.
University of Dundee · GBNewcastle University · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Liposome-microbubble conjugates are considered as better targeted drug delivery vehicles compared to microbubbles alone. The microbubble in the integrated drug delivery system delivers the drug intracellularly on the target, whereas the liposome component allows loading of high drug dose and extravasation through leaky vasculature. In this work, a new high yielding microbubble production method was used to prepare microbubbles for formulation of the liposome-conjugated drug delivery system. In formulation process, the prepared liposome of 200 nm diameter was attached to the microbubble surface using the avidin-biotin interaction. The analysis of the confocal scanning laser microscope images showed that approximately 8 × 10

Indexed as

Confocal scanning laser microscopy (CSLM)Image correlation spectroscopy (ICS)Liposome-microbubble conjugate

Identifiers

PMID29942387
PMCPMC5998260
OpenAlexW2570588074

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.