Evidence map›Paper›PMID 29942267›Full record

ArticleFrontiers in psychiatry2018

Neural Correlates of Moral Evaluation and Psychopathic Traits in Male Multi-Problem Young Adults.

Josjan Zijlmans, Reshmi Marhe, Floor Bevaart, Marie-Jolette A Luijks, Laura van Duin, Henning Tiemeier, Arne Popma

Open access · goldAbstract read
In one paragraph

Article in Frontiers in psychiatry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 3 pooled it
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 3 syntheses or guidelines pooled it, 19 citations in OpenAlex.

  1. Pooled it
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  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Josjan ZijlmansDepartment of Child and Adolescent Psychiatry, VU University Medical Center, Amsterdam, Netherlands.
Reshmi MarheDepartment of Child and Adolescent Psychiatry, VU University Medical Center, Amsterdam, Netherlands.
Floor BevaartDepartment of Child and Adolescent Psychiatry, VU University Medical Center, Amsterdam, Netherlands.
Marie-Jolette A LuijksDepartment of Child and Adolescent Psychiatry, VU University Medical Center, Amsterdam, Netherlands.
Laura van DuinDepartment of Child and Adolescent Psychiatry, VU University Medical Center, Amsterdam, Netherlands.
Henning TiemeierDepartment of Social and Behavioral Sciences, Harvard T.H. Chan School of Public Health, Boston, MA, United States.
Arne PopmaDepartment of Child and Adolescent Psychiatry, VU University Medical Center, Amsterdam, Netherlands.
Amsterdam UMC Location VUmc · NLErasmus MC · NLLeiden University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multi-problem young adults (18-27 years) present with a plethora of problems, including varying degrees of psychopathic traits. The amygdala and ventromedial prefrontal cortex (vmPFC) have been implicated in moral dysfunction in psychopathy in adolescents and adults, but no studies have been performed in populations in the transitional period to adulthood. We tested in multi-problem young adults the hypothesis that psychopathic traits are related to amygdala and vmPFC activity during moral evaluation. Additionally, we explored the relation between psychopathic traits and other regions consistently implicated in moral evaluation. Our final sample consisted of 100 multi-problem young adults and 22 healthy controls. During fMRI scanning, participants judged whether pictures showed a moral violation on a 1-4 scale. Whole brain analysis revealed neural correlates of moral evaluation consistent with the literature. Region of interest analyses revealed positive associations between the affective callous-unemotional dimension of psychopathy and activation in the left vmPFC, left superior temporal gyrus, and left cingulate. Our results are consistent with altered vmPFC function during moral evaluation in psychopathy, but we did not find evidence for amygdala involvement. Our findings indicate the affective callous-unemotional trait of psychopathy may be related to widespread altered activation patterns during moral evaluation in multi-problem young adults.

Indexed as

amygdalafMRImoralitypsychopathyventromedial prefrontal cortexyoung adulthood

Identifiers

PMID29942267
PMCPMC6004505
OpenAlexW2806827692

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.