Evidence map›Paper›PMID 29942257›Full record

ArticleFrontiers in pharmacology2018

Pharmacokinetics of Human Red Blood Cell Microparticles Prepared Using High-Pressure Extrusion Method.

Wenche Jy, Ashish K Rehni, Carlos Bidot, Hever Navarro-Quero, Conner R Haase, Sebastian Koch, Yeon S Ahn, Kunjan R Dave

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Wenche JyWallace H. Coulter Platelet Laboratory, Division of Hematology and Oncology, Department of Medicine, Miller School of Medicine, University of Miami, Miami, FL, United States.
Ashish K RehniCerebral Vascular Disease Research Laboratories, Miller School of Medicine, University of Miami, Miami, FL, United States.
Carlos BidotWallace H. Coulter Platelet Laboratory, Division of Hematology and Oncology, Department of Medicine, Miller School of Medicine, University of Miami, Miami, FL, United States.
Hever Navarro-QueroWallace H. Coulter Platelet Laboratory, Division of Hematology and Oncology, Department of Medicine, Miller School of Medicine, University of Miami, Miami, FL, United States.
Conner R HaaseCerebral Vascular Disease Research Laboratories, Miller School of Medicine, University of Miami, Miami, FL, United States.
Sebastian KochDepartment of Neurology, Miller School of Medicine, University of Miami, Miami, FL, United States.
Yeon S AhnWallace H. Coulter Platelet Laboratory, Division of Hematology and Oncology, Department of Medicine, Miller School of Medicine, University of Miami, Miami, FL, United States.
Kunjan R DaveCerebral Vascular Disease Research Laboratories, Miller School of Medicine, University of Miami, Miami, FL, United States.

Funding

Red blood cell microparticles (RMPs) to reduce bleeding following hemorrhagic strokeR33NS094896 · NINDS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI DAVE, KUNJAN R · 2017 to 2018
$835k
Red blood cell microparticles (RMPs) to reduce bleeding following hemorrhagic strokeR21NS094896 · NINDS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI DAVE, KUNJAN R · 2016 to 2016
$307k
NINDS NIH HHS R21 NS094896NINDS NIH HHS R33 NS094896
6 · The paper itself

Abstract

Red blood cell microparticles (RMPs) is a high potency hemostatic agent, which may serve as a viable therapeutic approach. They generate thrombin

Indexed as

dose responsehalf-lifehemostasisparticle sizeshelf-lifevolume of distribution

Identifiers

PMID29942257
PMCPMC6004370

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.