Evidence map›Paper›PMID 29942120›Full record

SynthesisClinical interventions in aging2018

Rainer Spiegel, Roger Kalla, Georgios Mantokoudis, Raphael Maire, Heiko Mueller, Robert Hoerr, Ralf Ihl

Open access · goldAbstract readMeta-AnalysisReview
In one paragraph

Synthesis in Clinical interventions in aging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 3 pooled it
4.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 3 syntheses or guidelines pooled it, 47 citations in OpenAlex.

  1. Efficacy and safety ofPharmaceutical biology · 2023
    Pooled it
  2. Ginkgo biloba for tinnitus.The Cochrane database of systematic reviews · 2022
    Pooled it
  3. Guideline
  4. Trial
  5. Efficacy of EGb 761Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale
    Trial
  6. Article
  7. Article
  8. Article
  9. Frontiers in neurology · 2024
    Article
  10. Article
  11. Review
  12. Review
  13. TiOAdvances in neurobiology · 2023
    Review
  14. Review
  15. Migrainous Vertigo, Tinnitus, and Ear Symptoms and Alternatives.Otolaryngologic clinics of North America · 2022
    Review
  16. Review
  17. Review
  18. Frontiers in pharmacology · 2022
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Rainer SpiegelDivision of Internal Medicine, Basel University Hospital, University of Basel, Basel, Switzerland.
Roger KallaDepartment of Neurology, Inselspital, Bern University Hospital, Bern, Switzerland.
Georgios MantokoudisDepartment of Otorhinolaryngology, Head and Neck Surgery, Inselspital, Bern University Hospital, Bern, Switzerland.
Raphael MaireLausanne University Hospital, Lausanne, Switzerland.
Heiko MuellerClinical Research Department, Dr Willmar Schwabe GmbH & Co. KG, Karlsruhe, Germany.
Robert HoerrClinical Research Department, Dr Willmar Schwabe GmbH & Co. KG, Karlsruhe, Germany.
Ralf IhlDepartment of Psychiatry, University of Duesseldorf, Alexian Research Center Krefeld, Krefeld, Germany.
Dr Willmar Schwabe (Germany) · DEUniversity Hospital of Bern · CHHelios Klinikum Krefeld · DEUniversity of Basel · CHUniversity of Lausanne · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTinnitus and dizziness are frequent in old age and often seen as concomitant symptoms in patients with dementia. In earlier clinical trials,

methodsRandomized, placebo-controlled clinical trials of

resultsFive trials that met the inclusion criteria were included in the meta-analysis. The risk of bias was judged as low, with Jadad scores of 3 and 5. In all trials, 11-point box scales were used to assess the severity of tinnitus and dizziness. Overall, EGb 761

conclusionOur findings support the notion that EGb 761

Indexed as

AgedDementiaDizzinessGaitGinkgo bilobaGinkgo ExtractHumansMaleMiddle AgedOutcome Assessment, Health CarePhytotherapyPlant ExtractsRandomized Controlled Trials as TopicTinnitusGinkgo biloba extractGinkgo ExtractPlant Extractsgaithearinginner earneurodegenerative disordersreviewunsteadiness

Identifiers

PMID29942120
PMCPMC6005330
OpenAlexW2808280078

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.