ArticleThe ISME journal2018
Genetic variability and ontogeny predict microbiome structure in a disease-challenged montane amphibian.
Article in The ISME journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed.
- MHC class II genes influence the gut microbiota of wild golden snub-nosed monkeys.BMC microbiology · 2026Article
- Bsal susceptibility depends on host origin but not on skin microbiota in captive Pleurodeles waltl.Animal microbiome · 2025Article
- Article
- Uropygial gland microbiota of nearctic-neotropical migrants vary with season and migration distance.Animal microbiome · 2025Article
- Archival mitogenomes identify invasion by theProceedings. Biological sciences · 2024Article
- Nor climate nor human impact factors: Chytrid infection shapes the skin bacterial communities of an endemic amphibian in a biodiversity hotspot.Ecology and evolution · 2024Article
- Environment predictsEcology and evolution · 2024Article
- From Alien Species to Alien Communities: Host- and Habitat-Associated Microbiomes in an Alien Amphibian.Microbial ecology · 2023Article
- Ontogeny drives shifts in skin bacterial communities in facultatively paedomorphic salamanders.Microbiology (Reading, England) · 2023Article
- Environmental and Anthropogenic Factors Shape the Skin Bacterial Communities of a Semi-Arid Amphibian Species.Microbial ecology · 2023Article
- The succession of gut microbiota in the concave-eared torrent frog (Ecology and evolution · 2023Article
- Neotropical Frog Foam Nest's Microbiomes.Microorganisms · 2023Article
- Signatures of functional bacteriome structure in a tropical direct-developing amphibian species.Animal microbiome · 2022Article
- Gut microbiota of ring-tailed lemurs (Lemur catta) vary across natural and captive populations and correlate with environmental microbiota.Animal microbiome · 2022Article
- Population Differences and Host Species Predict Variation in the Diversity of Host-Associated Microbes inFrontiers in microbiology · 2022Article
- Fungal microbiomes are determined by host phylogeny and exhibit widespread associations with the bacterial microbiome.Proceedings. Biological sciences · 2021Article
- Geography, Host Genetics, and Cross-Domain Microbial Networks Structure the Skin Microbiota of Fragmented Brazilian Atlantic Forest Frog Populations.Ecology and evolution · 2021Article
- Comparative hologenomics of twoPeerJ · 2021Article
- Mechanisms governing avian phylosymbiosis: Genetic dissimilarity based on neutral and MHC regions exhibits little relationship with gut microbiome distributions of Galápagos mockingbirds.Ecology and evolution · 2020Article
- Chytrid fungi and global amphibian declines.Nature reviews. Microbiology · 2020Review
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Amphibian populations worldwide are at risk of extinction from infectious diseases, including chytridiomycosis caused by the fungal pathogen Batrachochytrium dendrobatidis (Bd). Amphibian cutaneous microbiomes interact with Bd and can confer protective benefits to the host. The composition of the microbiome itself is influenced by many environment- and host-related factors. However, little is known about the interacting effects of host population structure, genetic variation and developmental stage on microbiome composition and Bd prevalence across multiple sites. Here we explore these questions in Amietia hymenopus, a disease-affected frog in southern Africa. We use microsatellite genotyping and 16S amplicon sequencing to show that the microbiome associated with tadpole mouthparts is structured spatially, and is influenced by host genotype and developmental stage. We observed strong genetic structure in host populations based on rivers and geographic distances, but this did not correspond to spatial patterns in microbiome composition. These results indicate that demographic and host genetic factors affect microbiome composition within sites, but different factors are responsible for host population structure and microbiome structure at the between-site level. Our results help to elucidate complex within- and among- population drivers of microbiome structure in amphibian populations. That there is a genetic basis to microbiome composition in amphibians could help to inform amphibian conservation efforts against infectious diseases.
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