Evidence map›Paper›PMID 29942032›Full record

ArticleScientific reports2018

A novel adenovirus isolated from the Egyptian fruit bat in South Africa is closely related to recent isolates from China.

Petrus Jansen van Vuren, Mushal Allam, Michael R Wiley, Arshad Ismail, Nadia Storm, Monica Birkhead, Wanda Markotter, Gustavo Palacios, Janusz T Paweska

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Identification of a novel adenovirus in liver tissue sample of the Great Himalayan leaf-nosed bat (Hipposideros armiger).Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024
    Article
  6. Article
  7. Article
  8. Viruses · 2022
    Article
  9. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Petrus Jansen van VurenCentre for Emerging Zoonotic and Parasitic Diseases, National Institute for Communicable Diseases of the National Health Laboratory Service, Sandringham, Johannesburg, South Africa.ORCID 0000-0003-2862-7983
Mushal AllamCore Sequencing Facility, National Institute for Communicable Diseases of the National Health Laboratory Service, Sandringham, Johannesburg, South Africa.ORCID 0000-0002-9875-6716
Michael R WileyCenter for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, USA.
Arshad IsmailCore Sequencing Facility, National Institute for Communicable Diseases of the National Health Laboratory Service, Sandringham, Johannesburg, South Africa.
Nadia StormCentre for Emerging Zoonotic and Parasitic Diseases, National Institute for Communicable Diseases of the National Health Laboratory Service, Sandringham, Johannesburg, South Africa.
Monica BirkheadCentre for Emerging Zoonotic and Parasitic Diseases, National Institute for Communicable Diseases of the National Health Laboratory Service, Sandringham, Johannesburg, South Africa.
Wanda MarkotterCentre for Viral Zoonoses, Department of Medical Virology, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa.
Gustavo PalaciosCenter for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, USA.ORCID 0000-0001-5062-1938
Janusz T PaweskaCentre for Emerging Zoonotic and Parasitic Diseases, National Institute for Communicable Diseases of the National Health Laboratory Service, Sandringham, Johannesburg, South Africa. januszp@nicd.ac.za.ORCID 0000-0001-8776-7519
National Health Laboratory Service · ZAUnited States Army Medical Research Institute of Infectious Diseases · USUniversity of Pretoria · ZA

Funding

CGH CDC HHS U19 GH000571
6 · The paper itself

Abstract

Recently a number of novel adenoviruses have been isolated from diverse bat species and from diverse geographical locations. We describe the isolation of a novel adenovirus (Family Adenoviridae, genus Mastadenovirus) from a pool of liver and spleen tissue of an apparently healthy wild-caught Egyptian fruit bat (Rousettus aegyptiacus) in South Africa. Genetically the virus is most closely related to four mastadenoviruses recently isolated in China, from Miniopterus schreibersi and Rousettus leschenaultii bats, which are highly divergent from previously identified bat adenoviruses. The length of the Rousettus aegyptiacus adenovirus-3085 (RaegAdV-3085) genome, at 29,342 bp is similar to its closest relatives, and contains 27 open reading frames. The RaegAdV-3085 genome has a low G + C content (36.4%) relative to other viruses in the genus (between 43.6 and 63.9%) but similar to its closest relatives. The inverted terminal repeat (ITR) of RaegAdV-3085 is only 40 bp compared to between 61 and 178 bp of its closest relatives. The discovery of RaegAdV-3085 expands the diversity of known adenoviruses in bats and might represent a member of a new mastadenovirus species in bats.

Indexed as

AdenoviridaeAnimalsChinaChiropteraHigh-Throughput Nucleotide SequencingHumansLiverPhylogenySouth AfricaSpleenWhole Genome Sequencing

Identifiers

PMID29942032
PMCPMC6018157
OpenAlexW2808805056

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.