Evidence map›Paper›PMID 29941917›Full record

ArticleNature structural & molecular biology2018

A CLC-type F

Nicholas B Last, Randy B Stockbridge, Ashley E Wilson, Tania Shane, Ludmila Kolmakova-Partensky, Akiko Koide, Shohei Koide, Christopher Miller

Open access · greenAbstract read
In one paragraph

Article in Nature structural & molecular biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 41 citations in OpenAlex.

  1. Review
  2. CLCEnvironmental microbiology · 2026
    Article
  3. Adaptive evolution ofJournal of bacteriology · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Fluoride Ion Binding and Translocation in the CLCThe journal of physical chemistry. B · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Fluoride Transport and Inhibition Across CLC Transporters.Handbook of experimental pharmacology · 2024
    Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Membrane Exporters of Fluoride Ion.Annual review of biochemistry · 2021
    Review
  19. Article
  20. Divergent CleLife · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Nicholas B LastDepartment of Biochemistry, Howard Hughes Medical Institute, Brandeis University, Waltham, MA, USA.
Randy B StockbridgeDepartment of Biochemistry, Howard Hughes Medical Institute, Brandeis University, Waltham, MA, USA.ORCID 0000-0001-8848-3032
Ashley E WilsonDepartment of Biochemistry, Howard Hughes Medical Institute, Brandeis University, Waltham, MA, USA.
Tania ShaneDepartment of Biochemistry, Howard Hughes Medical Institute, Brandeis University, Waltham, MA, USA.
Ludmila Kolmakova-PartenskyDepartment of Biochemistry, Howard Hughes Medical Institute, Brandeis University, Waltham, MA, USA.
Akiko KoidePerlmutter Cancer Center, New York University Langone Health, New York University School of Medicine, New York, NY, USA.
Shohei KoidePerlmutter Cancer Center, New York University Langone Health, New York University School of Medicine, New York, NY, USA.ORCID 0000-0001-5473-4358
Christopher MillerDepartment of Biochemistry, Howard Hughes Medical Institute, Brandeis University, Waltham, MA, USA. cmiller@brandeis.edu.ORCID 0000-0002-0273-8653
Howard Hughes Medical Institute · USNYU Langone Health · US

Funding

Synthetic Antigen Binder CoreU54GM087519 · NIGMS · UNIVERSITY OF CHICAGO · PI NAKAMOTO, ROBERT K. · 2010 to 2017
$31.9M
Macromolecular Structure MechanismT32GM007596 · NIGMS · BRANDEIS UNIVERSITY · PI OPRIAN, DANIEL D · 1985 to 2019
$4.5M
Structural and functional analysis of novel microbial membrane proteinsR35GM128768 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Randy B. Stockbridge · 2018 to 2026
$3.7M
Mechanisms of Biological Fluoride Resistance ExportersR01GM107023 · NIGMS · BRANDEIS UNIVERSITY · PI MILLER, CHRISTOPHER · 2014 to 2017
$1.1M
Pilatus 6mS10OD021832 · OD · UNIVERSITY OF CALIFORNIA BERKELEY · PI ADAMS, PAUL DAVID · 2016 to 2016
$980k
Howard Hughes Medical InstituteNIGMS NIH HHS R01 GM107023NIGMS NIH HHS R35 GM128768NIGMS NIH HHS T32 GM007596NIGMS NIH HHS U54 GM087519NIH HHS S10 OD021832
6 · The paper itself

Abstract

Fluoride/proton antiporters of the CLC

Indexed as

Amino Acid SubstitutionAntiportersBacterial ProteinsCrystallography, X-RayEnterococcusFluoridesGlutamic AcidIon TransportKineticsModels, BiologicalMutagenesis, Site-DirectedProtein ConformationProtein SubunitsProtonsAntiportersBacterial ProteinsFluoridesGlutamic AcidProtein SubunitsProtons

Identifiers

PMID29941917
PMCPMC6044475
OpenAlexW2808791900

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.