SynthesisEuropean journal of clinical nutrition2019
Polyphenol-rich foods and risk of gestational diabetes: a systematic review and meta-analysis.
Synthesis in European journal of clinical nutrition, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 4 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
32 citing papers in PubMed, 4 syntheses or guidelines pooled it, 58 citations in OpenAlex.
- Pooled it
- Polyphenol Intake in Pregnant Women on Gestational Diabetes Risk and Neurodevelopmental Disorders in Offspring: A Systematic Review.Nutrients · 2022Pooled it
- Pooled it
- Combined effect of interventions with pure or enriched mixtures of (poly)phenols and anti-diabetic medication in type 2 diabetes management: a meta-analysis of randomized controlled human trials.European journal of nutrition · 2020Pooled it
- Gestational Diabetes Mellitus: Efficacy of Non-Pharmacological Interventions for Management and Prevention.Healthcare (Basel, Switzerland) · 2025Review
- Adherence to plant-based diet during pregnancy and risk of gestational diabetes: a prospective birth cohort study.BMC nutrition · 2024Article
- The potential causal effect of the pre-pregnancy dietary phytochemical index on gestational diabetes mellitus: a prospective cohort study.BMC pregnancy and childbirth · 2024Article
- Article
- Gestational Diabetes and the Gut Microbiota: Fibre and Polyphenol Supplementation as a Therapeutic Strategy.Microorganisms · 2024Review
- Dietary protein in early pregnancy and gestational diabetes mellitus: a prospective cohort study.Endocrine · 2024Article
- Mineral Content and Phytochemical Composition of Avocado var. Hass Grown Using Sustainable Agriculture Practices in Ecuador.Plants (Basel, Switzerland) · 2023Article
- The Role of Lifestyle Interventions in the Prevention and Treatment of Gestational Diabetes Mellitus.Medicina (Kaunas, Lithuania) · 2023Review
- Bioactive Compounds from Fruits as Preservatives.Foods (Basel, Switzerland) · 2023Review
- Review
- Association of Polyphenols Consumption with Risk for Gestational Diabetes Mellitus and Preeclampsia: A Systematic Review and Meta-Analysis.Antioxidants (Basel, Switzerland) · 2022Article
- Evidence for Quercetin as a Dietary Supplement for the Treatment of Cardio-Metabolic Diseases in Pregnancy: A Review in Rodent Models.Foods (Basel, Switzerland) · 2022Review
- Phytochemical Composition and Antioxidant Activity ofPlants (Basel, Switzerland) · 2022Article
- Investigating Polyphenol Nanoformulations for Therapeutic Targets against Diabetes Mellitus.Evidence-based complementary and alternative medicine : eCAM · 2022Review
- Modulatory Impact of Lamiaceae Metabolites on Apoptosis of Human Leukemia Cells.Frontiers in pharmacology · 2022Article
- Dietary Intake in Early Pregnancy and Glycemia in Late Pregnancy among Women with Obesity.Nutrients · 2021Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Animal studies have demonstrated anti-diabetic properties of several food-derived polyphenols, but data in humans remains unclear. This study aimed to review and meta-analyse evidence concerning the effect of the intake of several polyphenol-rich foods on gestational diabetes (GDM) risk. A systematic literature search was conducted in PubMed, Web of Science and Embase databases for observational studies on the association between dietary intake of foods/diets rich in polyphenols and GDM risk. Inclusion criteria were original research articles with full texts published in peer-reviewed English language journals, which investigated foods within the top 100 richest dietary sources of polyphenols and reported odds ratio/relative risk with their corresponding 95% confidence intervals. The quality of included studies was assessed using the Newcastle-Ottawa Scale. The intake of polyphenol-rich foods and dietary patterns in relation to GDM were pooled with fixed- and random-effects models. In total, 12 (10 cohort, 1 cross-sectional and 1 case-control) studies were included for the final systematic review, comprising 124,959 participants and including 5,786 women with GDM. Five studies found a significant, inverse association between the intake of polyphenol-rich foods or Mediterranean diet and GDM, whereas five studies reported no association and two exhibited a positive association. Meta-analyses further showed that the risk of GDM was about halved amongst women with the highest score of Mediterranean diet compared to those with the lowest score. The results suggest that dietary patterns rich in polyphenols may reduce the risk of GDM despite inconclusive evidence for polyphenol-rich food groups.
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Registered trials
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