Evidence map›Paper›PMID 29941867›Full record

ArticleScientific reports2018

Association of microRNA-7 and its binding partner CDR1-AS with the prognosis and prediction of 1

K Uhr, A M Sieuwerts, V de Weerd, M Smid, D Hammerl, J A Foekens, J W M Martens

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 4 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 4 syntheses or guidelines pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Review
  6. Article
  7. Dual effects of circRNA in thyroid and breast cancer.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2023
    Review
  8. Review
  9. Emerging roles of circular RNAs in retinal diseases.Neural regeneration research · 2022
    Review
  10. The emerging roles of circRNAs in cancer and oncology.Nature reviews. Clinical oncology · 2022
    Review
  11. Review
  12. Review
  13. Article
  14. Review
  15. The Use of circRNAs as Biomarkers of Cancer.Methods in molecular biology (Clifton, N.J.) · 2021
    Review
  16. Review
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

K UhrErasmus MC Cancer Institute, Erasmus University Medical Centre, Department of Medical Oncology and Cancer Genomics, Wytemaweg 80, 3015 CN, Rotterdam, The Netherlands.ORCID 0000-0001-5637-9564
A M SieuwertsErasmus MC Cancer Institute, Erasmus University Medical Centre, Department of Medical Oncology and Cancer Genomics, Wytemaweg 80, 3015 CN, Rotterdam, The Netherlands. a.sieuwerts@erasmusmc.nl.ORCID 0000-0003-1341-5400
V de WeerdErasmus MC Cancer Institute, Erasmus University Medical Centre, Department of Medical Oncology and Cancer Genomics, Wytemaweg 80, 3015 CN, Rotterdam, The Netherlands.
M SmidErasmus MC Cancer Institute, Erasmus University Medical Centre, Department of Medical Oncology and Cancer Genomics, Wytemaweg 80, 3015 CN, Rotterdam, The Netherlands.
D HammerlErasmus MC Cancer Institute, Erasmus University Medical Centre, Department of Medical Oncology and Cancer Genomics, Wytemaweg 80, 3015 CN, Rotterdam, The Netherlands.
J A FoekensErasmus MC Cancer Institute, Erasmus University Medical Centre, Department of Medical Oncology and Cancer Genomics, Wytemaweg 80, 3015 CN, Rotterdam, The Netherlands.
J W M MartensErasmus MC Cancer Institute, Erasmus University Medical Centre, Department of Medical Oncology and Cancer Genomics, Wytemaweg 80, 3015 CN, Rotterdam, The Netherlands.ORCID 0000-0002-3428-3366
Erasmus MC Cancer Institute · NL

Funding

European Research Council 322737
6 · The paper itself

Abstract

The large number of non-coding RNAs (ncRNAs) and their breadth of functionalities has fuelled many studies on their roles in cancer. We previously linked four microRNAs to breast cancer prognosis. One of these microRNAs, hsa-miR-7, was found to be regulated by another type of ncRNA, the circular non-coding RNA (circRNA) CDR1-AS, which contains multiple hsa-miR-7 binding sites. Based on this finding, we studied the potential clinical value of this circRNA on breast cancer prognosis in a cohort based on a cohort that was previously analysed for hsa-miR-7 and in an adjuvant hormone-naïve cohort for 1

Indexed as

AdultAgedBreast NeoplasmsCell Line, TumorDisease-Free SurvivalGene Expression Regulation, NeoplasticHumansMicroRNAsMiddle AgedRecurrenceRNA, Long NoncodingTamoxifenlong non-coding RNA CDR1AS, humanMicroRNAsMIRN7-1 microRNA, humanRNA, Long NoncodingTamoxifen

Identifiers

PMID29941867
PMCPMC6018428
OpenAlexW2809473092

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.