Evidence map›Paper›PMID 29941646›Full record

ArticleAntimicrobial agents and chemotherapy2018

Pharmacokinetics and Comprehensive Analysis of the Tissue Distribution of Eravacycline in Rabbits.

Vidmantas Petraitis, Ruta Petraitiene, Bo Bo W Maung, Farehin Khan, Ieva Alisauskaite, Melanie Olesky, Joseph Newman, Abdul Mutlib, Xiaoyun Niu, Michael Satlin and 3 more

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Article
  3. Managing skin infections in burn patients: principles and pitfalls.Current opinion in infectious diseases · 2026
    Review
  4. Article
  5. Article
  6. NDM-ProducingFrontiers in medicine · 2026
    Article
  7. Antimicrobial agents and chemotherapy · 2025
    Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Vidmantas PetraitisTransplantation-Oncology Infectious Diseases Program, Division of Infectious Diseases, Department of Medicine, Weill Cornell Medicine of Cornell University, New York, New York, USA vip2007@med.cornell.edu.
Ruta PetraitieneTransplantation-Oncology Infectious Diseases Program, Division of Infectious Diseases, Department of Medicine, Weill Cornell Medicine of Cornell University, New York, New York, USA.
Bo Bo W MaungTransplantation-Oncology Infectious Diseases Program, Division of Infectious Diseases, Department of Medicine, Weill Cornell Medicine of Cornell University, New York, New York, USA.
Farehin KhanTransplantation-Oncology Infectious Diseases Program, Division of Infectious Diseases, Department of Medicine, Weill Cornell Medicine of Cornell University, New York, New York, USA.
Ieva AlisauskaiteTransplantation-Oncology Infectious Diseases Program, Division of Infectious Diseases, Department of Medicine, Weill Cornell Medicine of Cornell University, New York, New York, USA.
Melanie OleskyTetraphase Pharmaceuticals, Watertown, Massachusetts, USA.
Joseph NewmanTetraphase Pharmaceuticals, Watertown, Massachusetts, USA.
Abdul MutlibFrontage, Exton, Pennsylvania, USA.
Xiaoyun NiuFrontage, Exton, Pennsylvania, USA.
Michael SatlinTransplantation-Oncology Infectious Diseases Program, Division of Infectious Diseases, Department of Medicine, Weill Cornell Medicine of Cornell University, New York, New York, USA.
Ravi S SinghDepartment of Pharmaceutics, College of Pharmacy, University of Florida, Gainesville, Florida, USA.
Harmut DerendorfDepartment of Pharmaceutics, College of Pharmacy, University of Florida, Gainesville, Florida, USA.
Thomas J WalshTransplantation-Oncology Infectious Diseases Program, Division of Infectious Diseases, Department of Medicine, Weill Cornell Medicine of Cornell University, New York, New York, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Eravacycline (7-fluoro-9-pyrrolidinoacetamido-6-demethyl-6-deoxytetracycline or TP-434) is a novel, fully synthetic broad-spectrum fluorocycline with potent activity against Gram-positive bacteria, anaerobes, and multidrug-resistant

Indexed as

AnimalsAnti-Bacterial AgentsArea Under CurveDrug Resistance, Multiple, BacterialEnterobacteriaceaeFemaleGram-Positive BacteriaMaleMicrobial Sensitivity TestsRabbitsTetracyclinesTissue DistributionAnti-Bacterial AgentseravacyclineTetracyclineseravacyclinepharmacokineticsrabbitstissue distribution

Identifiers

PMID29941646
PMCPMC6125520

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.