Evidence map›Paper›PMID 29941619›Full record

ArticleGenetics2018

Initiation of Meiotic Development Is Controlled by Three Post-transcriptional Pathways in

Ariz Mohammad, Kara Vanden Broek, Christopher Wang, Anahita Daryabeigi, Verena Jantsch, Dave Hansen, Tim Schedl

Open access · bronzeAbstract read
In one paragraph

Article in Genetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 46 citations in OpenAlex.

  1. Active maintenance of meiosis-specific chromosome structures inProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Review
  3. Article
  4. Active maintenance of meiosis-specific chromosome structures inbioRxiv : the preprint server for biology · 2025
    Article
  5. Article
  6. Article
  7. Notch controls APC/CScience advances · 2025
    Article
  8. Article
  9. Analysis of the C. elegans Germline Stem Cell Pool.Methods in molecular biology (Clifton, N.J.) · 2023
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Functional Modules in Gametogenesis.Frontiers in cell and developmental biology · 2022
    Article
  18. Review
  19. Article
  20. SCFLife science alliance · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Ariz MohammadDepartment of Genetics, School of Medicine, Washington University in St. Louis, Missouri 63110.
Kara Vanden BroekDepartment of Biological Sciences, University of Calgary, T2N 1N4, Canada.
Christopher WangDepartment of Biological Sciences, University of Calgary, T2N 1N4, Canada.
Anahita DaryabeigiDepartment of Chromosome Biology, Max F. Perutz Laboratories, University of Vienna, Vienna Biocenter, 1030, Austria.
Verena JantschDepartment of Chromosome Biology, Max F. Perutz Laboratories, University of Vienna, Vienna Biocenter, 1030, Austria.ORCID 0000-0002-1978-682X
Dave HansenDepartment of Biological Sciences, University of Calgary, T2N 1N4, Canada.
Tim SchedlDepartment of Genetics, School of Medicine, Washington University in St. Louis, Missouri 63110 ts@genetics.wustl.edu.
University of Calgary · CAWashington University in St. Louis · USMax Perutz Labs · ATVienna Biocenter · AT

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
Stem cell versus meiotic fate decision in C. elegansR01GM100756 · NIGMS · WASHINGTON UNIVERSITY · PI SCHEDL, TIM · 2012 to 2023
$4.2M
NIGMS NIH HHS R01 GM100756NIH HHS P40 OD010440
6 · The paper itself

Abstract

A major event in germline development is the transition from stem/progenitor cells to entry into meiosis and gametogenesis. This transition requires downregulation of mitotic cell cycle activity and upregulation of processes associated with meiosis. We identify the

Indexed as

Gene Regulatory NetworksMeiosisSignal TransductionAnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsCell Cycle ProteinsCheckpoint Kinase 2Drosophila ProteinsF-Box ProteinsGametogenesisGene Expression RegulationPolynucleotide AdenylyltransferaseProtein BiosynthesisProteolysisReceptors, NotchCaenorhabditis elegans ProteinsCell Cycle ProteinsCheckpoint Kinase 2CHK-2 protein, C elegansDrosophila ProteinsF-Box ProteinsGLD-1 protein, C elegansGLD-2 protein, C elegansN protein, DrosophilaPolynucleotide AdenylyltransferasePROM-1 protein, C elegansReceptors, NotchgermlineGLD-1GLD-2meiotic developmentmeiotic entryPROM-1SCF

Identifiers

PMID29941619
PMCPMC6063227
OpenAlexW2810064777

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.