Evidence map›Paper›PMID 29941569›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2018

Ionophoric effects of the antitubercular drug bedaquiline.

Kiel Hards, Duncan G G McMillan, Lici A Schurig-Briccio, Robert B Gennis, Holger Lill, Dirk Bald, Gregory M Cook

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 99 citations in OpenAlex.

  1. Article
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  5. Fighting Antimicrobial Resistance: Innovative Drugs in Antibacterial Research.Angewandte Chemie (International ed. in English) · 2025
    Review
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  7. Article
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  17. FInternational journal of molecular sciences · 2023
    Review
  18. Review
  19. Purine metabolism regulatesFrontiers in microbiology · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 3 countries.

Kiel HardsDepartment of Microbiology and Immunology, School of Biomedical Sciences, University of Otago, 9054 Dunedin, New Zealand.
Duncan G G McMillanDepartment of Biotechnology, Delft University of Technology, 2629 HZ Delft, The Netherlands.
Lici A Schurig-BriccioDepartment of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801.
Robert B GennisDepartment of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801.
Holger LillDepartment of Molecular Cell Biology, Amsterdam Institute for Molecules, Medicines and Systems, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands.
Dirk BaldDepartment of Molecular Cell Biology, Amsterdam Institute for Molecules, Medicines and Systems, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands.
Gregory M CookDepartment of Microbiology and Immunology, School of Biomedical Sciences, University of Otago, 9054 Dunedin, New Zealand; gregory.cook@otago.ac.nz.
University of Illinois Urbana-Champaign · USVrije Universiteit Amsterdam · NLDelft University of Technology · NLMaurice Wilkins Centre · NZUniversity of Otago · NZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bedaquiline (BDQ), an inhibitor of the mycobacterial F

Indexed as

Adenosine TriphosphateAntitubercular AgentsDiarylquinolinesEscherichia coliEscherichia coli ProteinsHydrogen-Ion ConcentrationIonophoresProton-Translocating ATPasesAdenosine TriphosphateAntitubercular AgentsbedaquilineDiarylquinolinesEscherichia coli ProteinsIonophoresProton-Translocating ATPasesbedaquilineionophorerespirationtuberculosisuncoupler

Identifiers

PMID29941569
PMCPMC6048524
OpenAlexW2809880794

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.