Trial reportHypertension (Dallas, Tex. : 1979)2018
Renin-Angiotensin-Aldosterone Profiles in Pregnant Women With Chronic Hypertension.
Trial report in Hypertension (Dallas, Tex. : 1979), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 42 citations in OpenAlex.
- Hypertension Management in Pregnancy and Postpartum.Journal of the American Society of Nephrology : JASN · 2026Review
- Antecedent of Pregnancy-Related Cardiometabolic Complication and Risk of Cardiovascular Disease Among Women With Type 2 Diabetes.Diabetes, obesity & metabolism · 2026Article
- Renin-Angiotensin-Aldosterone System in Preeclampsia: Pathophysiological Insights and Links to Vascular Dementia.Arteriosclerosis, thrombosis, and vascular biology · 2026Review
- Biomarkers and point of care screening approaches for the management of preeclampsia.Communications medicine · 2024Review
- Variable effect of the post-partum menstrual cycle on aldosterone and renin in women with recent preeclampsia.Journal of human hypertension · 2024Article
- Associations of salivary aldosterone levels during pregnancy with maternal blood pressure and birth weight-for-gestational age in a Mexico City birth cohort.Journal of perinatology : official journal of the California Perinatal Association · 2024Article
- Adverse pregnancy outcomes and renal-vascular function in the early years after delivery.American journal of physiology. Heart and circulatory physiology · 2024Article
- Rare case of steroid cell tumour presenting as resistant hypertension in early pregnancy.BMJ case reports · 2023Article
- Association of Elevated Serum Aldosterone Concentrations in Pregnancy with Hypertension.Biomedicines · 2023Article
- Activation of the Renin-Angiotensin-Aldosterone System Is Attenuated in Hypertensive Compared with Normotensive Pregnancy.International journal of molecular sciences · 2023Article
- Physiology of Pregnancy-Related Acute Kidney Injury.Comprehensive Physiology · 2023Article
- Incidence of Heart Failure Related to Co-Occurrence of Gestational Hypertensive Disorders and Gestational Diabetes.JACC. Advances · 2023Article
- Renal CD81 interacts with sodium potassium 2 chloride cotransporter and sodium chloride cotransporter in rats with lipopolysaccharide-induced preeclampsia.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2023Article
- Maternal fructose intake during pregnancy and lactation: Later effects on renal function.Physiological reports · 2022Article
- [Angiotensin Ⅱ inhibits AMPK/SIRT1 pathway by inducing oxidative stress in RAW264.7 macrophages].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2021Article
- Association of Hypertensive Disorders of Pregnancy With Left Ventricular Remodeling Later in Life.Journal of the American College of Cardiology · 2021Article
- TLR4 regulates vascular smooth muscle cell proliferation in hypertension via modulation of the NLRP3 inflammasome.American journal of translational research · 2021Article
- Moderate Physical Exercise Activates ATRFrontiers in physiology · 2021Article
- Article
- Responses of the renin-angiotensin-aldosterone system in pregnant chronic kidney disease patients with and without superimposed pre-eclampsia.Clinical kidney journal · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
Pregnant women with chronic hypertension are at risk for increased blood pressure and superimposed preeclampsia (SPE) in late pregnancy. Alterations in the renin-aldosterone system are a feature of normal pregnancy; however, their role in chronic hypertension with and without SPE is less clear. We performed a prospective, longitudinal trial of 108 women with chronic hypertension and measured plasma renin activity (PRA), 24-hour urine sodium, urine potassium, and urine aldosterone (Ualdo) at 12, 20, 28, and 36 weeks and postpartum. SPE developed in 34% of pregnancies. PRA was lower in women who developed SPE at weeks 28 (5.99 versus 6.22 ng/mL per hour;
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.