Evidence map›Paper›PMID 29941515›Full record

ArticleHypertension (Dallas, Tex. : 1979)2018

Adenosine Receptors Influence Hypertension in Dahl Salt-Sensitive Rats: Dependence on Receptor Subtype, Salt Diet, and Sex.

Edwin K Jackson, Delbert G Gillespie, Zaichuan Mi, Dongmei Cheng

Open access · bronzeAbstract read
In one paragraph

Article in Hypertension (Dallas, Tex. : 1979), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Sodium Intake and Target Organ Damage in Hypertension-An Update about the Role of a Real Villain.International journal of environmental research and public health · 2020
    Review
  17. Adenosine inhibits the basolateral ClAmerican journal of physiology. Renal physiology · 2020
    Article
  18. Review
  19. Adenosine, Via AHypertension (Dallas, Tex. : 1979) · 2020
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Edwin K JacksonFrom the Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, PA. edj@pitt.edu.
Delbert G GillespieFrom the Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, PA.
Zaichuan MiFrom the Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, PA.
Dongmei ChengFrom the Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, PA.
University of Pittsburgh · US

Funding

Single Nephron and MetabolomicsP30DK079307 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KLEYMAN, THOMAS R · 2008 to 2022
$13.4M
Gene targeted rat resource for the study of complex diseaseR24HL114474 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI DWINELL, MELINDA R · 2013 to 2017
$8.7M
Role of Renal Dipeptidyl Peptidase IVR01HL069846 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI JACKSON, EDWIN KERRY · 2003 to 2020
$6.6M
The Guanosine-Adenosine MechanismR01HL109002 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI JACKSON, EDWIN KERRY · 2012 to 2023
$5.1M
The Renal 2',3'-cAMP-Adenosine PathwayR01DK068575 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI JACKSON, EDWIN KERRY · 2005 to 2016
$4.0M
Adenosine in Renal Sympathetic NeurotransmissionR01DK091190 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI JACKSON, EDWIN KERRY · 2011 to 2020
$3.4M
NHLBI NIH HHS R01 HL069846NHLBI NIH HHS R01 HL109002NIDDK NIH HHS P30 DK079307NIDDK NIH HHS R01 DK068575NIDDK NIH HHS R01 DK091190
6 · The paper itself

Abstract

The influence of adenosine receptors on blood pressure in salt-sensitive hypertension is unknown. Here, we examined the effects of salt diets on arterial blood pressures (radiotelemetry) in female and male Dahl salt-sensitive wild-type versus female and male Dahl salt-sensitive A

Indexed as

Gene Expression RegulationAnimalsBlood PressureDiet, Sodium-RestrictedDisease Models, AnimalFemaleHypertensionMaleRatsRats, Inbred DahlReceptors, Purinergic P1Reverse Transcriptase Polymerase Chain ReactionRNASodium Chloride, DietaryReceptors, Purinergic P1RNASodium Chloride, Dietaryadenosineadenosine receptorsblood pressureDahl salt-sensitive ratshypertension

Identifiers

PMID29941515
PMCPMC6053282
OpenAlexW2810244063

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.