ArticleJournal of biomechanics2018
The interaction of muscle moment arm, knee laxity, and torque in a multi-scale musculoskeletal model of the lower limb.
Article in Journal of biomechanics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Computational biomechanics of human knee joint in maximum voluntary isometric extension with focus on the role of joint center positioning.Scientific reports · 2026Article
- A study on the effects of different isokinetic testing modes of knee flexion-extension muscle strength ratios on lower extremity stiffness during jumping.Scientific reports · 2025Article
- Recent developments in computational modelling of the knee.Osteoarthritis imaging · 2024Article
- Computational prediction of muscle synergy using a finite element framework for a musculoskeletal model on lower limb.Frontiers in bioengineering and biotechnology · 2023Article
- Modeling of active skeletal muscles: a 3D continuum approach incorporating multiple muscle interactions.Frontiers in bioengineering and biotechnology · 2023Article
- Quadriceps strength and knee joint function in patients with severe knee extension contracture following arthroscopic-assisted mini-incision quadricepsplasty.International orthopaedics · 2021Article
- Hamstrings Contraction Regulates the Magnitude and Timing of the Peak ACL Loading During the Drop Vertical Jump in Female Athletes.Orthopaedic journal of sports medicine · 2021Article
- Sarcomere length of the vastus intermedius with the knee joint angle change.Physiological reports · 2021Article
- Anterior Cruciate Ligament Loading Increases With Pivot-Shift Mechanism During Asymmetrical Drop Vertical Jump in Female Athletes.Orthopaedic journal of sports medicine · 2021Article
- Patellofemoral kinematics in healthy older adults during gait activities.Human movement science · 2021Article
- Calibration and validation of a novel hybrid model of the lumbosacral spine in ArtiSynth-The passive structures.PloS one · 2021Article
- ReadySim: A computational framework for building explicit finite element musculoskeletal simulations directly from motion laboratory data.International journal for numerical methods in biomedical engineering · 2020Article
- A computationally efficient strategy to estimate muscle forces in a finite element musculoskeletal model of the lower limb.Journal of biomechanics · 2019Article
- A lower extremity model for muscle-driven simulation of activity using explicit finite element modeling.Journal of biomechanics · 2019Article
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4 authors.
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Abstract
introductionMusculoskeletal modeling allows insight into the interaction of muscle force and knee joint kinematics that cannot be measured in the laboratory. However, musculoskeletal models of the lower extremity commonly use simplified representations of the knee that may limit analyses of the interaction between muscle forces and joint kinematics. The goal of this research was to demonstrate how muscle forces alter knee kinematics and consequently muscle moment arms and joint torque in a musculoskeletal model of the lower limb that includes a deformable representation of the knee.
methodsTwo musculoskeletal models of the lower limb including specimen-specific articular geometries and ligament deformability at the knee were built in a finite element framework and calibrated to match mean isometric torque data collected from 12 healthy subjects. Muscle moment arms were compared between simulations of passive knee flexion and maximum isometric knee extension and flexion. In addition, isometric torque results were compared with predictions using simplified knee models in which the deformability of the knee was removed and the kinematics at the joint were prescribed for all degrees of freedom.
resultsPeak isometric torque estimated with a deformable knee representation occurred between 45° and 60° in extension, and 45° in flexion. The maximum isometric flexion torques generated by the models with deformable ligaments were 14.6% and 17.9% larger than those generated by the models with prescribed kinematics; by contrast, the maximum isometric extension torques generated by the models were similar. The change in hamstrings moment arms during isometric flexion was greater than that of the quadriceps during isometric extension (a mean RMS difference of 9.8 mm compared to 2.9 mm, respectively). DISCUSSION: The large changes in the moment arms of the hamstrings, when activated in a model with deformable ligaments, resulted in changes to flexion torque. When simulating human motion, the inclusion of a deformable joint in a multi-scale musculoskeletal finite element model of the lower limb may preserve the realistic interaction of muscle force with knee kinematics and torque.
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