Evidence map›Paper›PMID 29941145›Full record

ArticleBiological psychiatry2018

The Class II Histone Deacetylase Hypothesis of Addiction.

Edmund A Griffin, Philippe A Melas, Denise B Kandel, Eric R Kandel

Abstract readComment
PubMed Publisher
In one paragraph

Article in Biological psychiatry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Cannabinoid exposure in rat adolescence reprograms the initial behavioral, molecular, and epigenetic response to cocaine.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Edmund A GriffinDepartment of Psychiatry, Columbia University, New York, New York; New York State Psychiatric Institute, New York, New York.
Philippe A MelasDepartment of Neuroscience, Columbia University, New York, New York; Mortimer B. Zuckerman Mind Brain Behavior Institute, Columbia University, New York, New York; Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Denise B KandelDepartment of Psychiatry, Columbia University, New York, New York; Mailman School of Public Health, Columbia University, New York, New York; New York State Psychiatric Institute, New York, New York.
Eric R KandelDepartment of Psychiatry, Columbia University, New York, New York; Department of Neuroscience, Columbia University, New York, New York; Mortimer B. Zuckerman Mind Brain Behavior Institute, Columbia University, New York, New York; Kavli Institute for Brain Science, Columbia University, New York, New York; Howard Hughes Medical Institute, Chevy Chase, Maryland. Electronic address: erk5@columbia.edu.

Funding

Howard Hughes Medical Institute
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Behavior, AddictiveMethamphetamineCravingHistone DeacetylasesHistone DeacetylasesMethamphetamine

Identifiers

PMID29941145

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.