Evidence map›Paper›PMID 29941003›Full record

Trial reportTrials2018

Speech-guided breathing retraining in asthma: a randomised controlled crossover trial in real-life outpatient settings.

Dietrich von Bonin, Sabine D Klein, Jana Würker, Eva Streit, Oliver Avianus, Christian Grah, Jörg Salomon, Ursula Wolf

Registry-linked trialOpen access · goldAbstract readMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Trials, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02501824 (Effectiveness of Anthroposophic Therapeutic Speech in Patients With Asthma in a Real-life Outpatient Setting - a Randomised, Controlled, Multicentre Cross-over Trial), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02501824 phase2completednot on this map

Effectiveness of Anthroposophic Therapeutic Speech in Patients With Asthma in a Real-life Outpatient Setting - a Randomised, Controlled, Multicentre Cross-over Trial

TypeinterventionalSponsorUniversity of BernRan2010 to 2014Enrolled49ConditionsAsthmaArmsanthroposophic therapeutic speech
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Trial
  2. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Dietrich von BoninInstitute of Complementary Medicine, University of Bern, Fabrikstrasse 8, 3012, Bern, Switzerland.
Sabine D KleinInstitute of Complementary Medicine, University of Bern, Fabrikstrasse 8, 3012, Bern, Switzerland.
Jana WürkerInstitute of Complementary Medicine, University of Bern, Fabrikstrasse 8, 3012, Bern, Switzerland.
Eva StreitKlinik Arlesheim, Arlesheim, Switzerland.
Oliver AvianusGemeinschaftskrankenhaus Havelhöhe, Clinic for Anthroposophical Medicine, Berlin, Germany.
Christian GrahGemeinschaftskrankenhaus Havelhöhe, Clinic for Anthroposophical Medicine, Berlin, Germany.
Jörg SalomonLungenZentrum Salem-Spital, Bern, Switzerland.
Ursula WolfInstitute of Complementary Medicine, University of Bern, Fabrikstrasse 8, 3012, Bern, Switzerland. ursula.wolf@ikom.unibe.ch.
University of Bern · CHGemeinschaftskrankenhaus Havelhöhe · DEHirslanden Salem-Spital · CHSwiss Institute for Art Research · CH

Funding

Legacy for this study through NiederKraftFrey, Zurich, Switzerland n.a.
6 · The paper itself

Abstract

backgroundBreathing retraining techniques have received increased attention in the management of asthma, because there is growing evidence of the usefulness of such methods in improving quality of life, reducing symptoms and reducing bronchodilator use. Our study investigated the effect of anthroposophic therapeutic speech (ATS), which uses sounds and syllabic rhythm to improve articulation, breathing and cardiorespiratory interaction, in patients with asthma in a real-life outpatient setting.

methodsIn a randomised controlled crossover trial, patients with asthma in three centres in Switzerland and Germany were randomised to either receive 11 ATS sessions or to wait. Subsequently, patients changed either to wait or to receive ATS. Primary outcomes were changes from the beginning to the end of each phase in the Asthma Quality of Life Questionnaire (AQLQ) and spirometry parameters. Secondary outcomes were changes in inhaled glucocorticoids, the Asthma Control Test (ACT), peak flow and asthma exacerbations.

resultsAltogether, 63 patients were randomised, of which 56 were enrolled and 49 completed the study. Statistically significant differences between the ATS groups and waiting control groups were found for the overall AQLQ score (d = 0.86, p = 0.001) and the domain scores for symptoms, activity limitation and emotional function as well as ACT score (d = 0.53, p = 0.048). No significant differences were observed in spirometry parameters, inhaled glucocorticoids, peak flow and days without asthma exacerbation per week. No serious adverse events occurred during ATS sessions.

conclusionsATS significantly improves asthma control and quality of life in patients with asthma. Whether ATS may improve lung function remains to be shown.

trial registrationClinicalTrials.gov NCT02501824 . Retrospectively registered on 8 July 2015.

Indexed as

Ambulatory CareAnthroposophyRespirationSpeechAdultAsthmaBreathing ExercisesCross-Over StudiesFemaleGermanyHumansLungMaleMiddle AgedQuality of LifeRecovery of FunctionAnthroposophic therapeutic speechAsthmaBreathingLung functionQuality of life

Identifiers

PMID29941003
PMCPMC6019518
OpenAlexW2810511914

What OpenQuestion holds

Textmetadata
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.