Evidence map›Paper›PMID 29940960›Full record

ArticlePediatric rheumatology online journal2018

Development of practice and consensus-based strategies including a treat-to-target approach for the management of moderate and severe juvenile dermatomyositis in Germany and Austria.

Claas H Hinze, Prasad T Oommen, Frank Dressler, Andreas Urban, Frank Weller-Heinemann, Fabian Speth, Elke Lainka, Jürgen Brunner, Heike Fesq, Dirk Foell and 6 more

Open access · goldAbstract readConsensus Statement
In one paragraph

Article in Pediatric rheumatology online journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 54 citations in OpenAlex.

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  17. Treatment of Calcinosis in Juvenile Dermatomyositis.Current rheumatology reports · 2021
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  18. Article
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  20. [Juvenile dermatomyositis-what's new?]Zeitschrift fur Rheumatologie · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 12 institutions in 4 countries.

Claas H HinzeDepartment of Pediatric Rheumatology and Immunology, University Hospital Münster, Albert-Schweitzer-Campus 1, Building D3, 48149, Münster, Germany. claas.hinze@ukmuenster.de.ORCID http://orcid.org/0000-0001-9247-4729
Prasad T OommenDepartment of Pediatric Oncology, Hematology and Clinical Immunology, University Hospital Düsseldorf, Düsseldorf, Germany.
Frank DresslerDepartment of Pediatric Pulmonology, Allergy and Neonatology, Hanover Medical School, Hanover, Germany.
Andreas UrbanDepartment of Pediatrics, St. Mary's Hospital, Amberg, Germany.
Frank Weller-HeinemannDivision of Pediatric Rheumatology, Prof. Hess Children's Hospital, Bremen, Germany.
Fabian SpethDivision of Pediatric Rheumatology, University Medicine, Rostock, Germany.
Elke LainkaDepartment of Pediatrics, University Hospital Essen, Essen, Germany.
Jürgen BrunnerDepartment of Pediatrics, Medical University Innsbruck, Innsbruck, Austria.
Heike FesqGerman Center for Pediatric and Adolescent Rheumatology, Garmisch-Partenkirchen Department of Dermatology, Oberammergau Center for Rheumatic Diseases, Oberammergau, Germany.
Dirk FoellDepartment of Pediatric Rheumatology and Immunology, University Hospital Münster, Albert-Schweitzer-Campus 1, Building D3, 48149, Münster, Germany.
Wolfgang Müller-FelberDepartment of Pediatric Neurology, University Hospital Munich, Munich, Germany.
Ulrich NeudorfDepartment of Pediatrics, University Hospital Essen, Essen, Germany.
Christoph RietschelDepartment of Pediatrics, Clementine Children's Hospital, Frankfurt, Germany.
Tobias SchwarzDepartment of Pediatric Rheumatology, St. Josef Hospital, Sendenhorst, Germany.
Ulrike ScharaDepartment of Pediatric Neurology, University Hospital Essen, Essen, Germany.
Johannes-Peter HaasGerman Center for Pediatric and Adolescent Rheumatology, Garmisch-Partenkirchen Department of Dermatology, Oberammergau Center for Rheumatic Diseases, Oberammergau, Germany.
Essen University Hospital · DEGerman Center for Pediatric and Adolescent Rheumatology · DEUniversity Hospital Münster · DEDüsseldorf University Hospital · DEInnsbruck Medical University · ATLMU Klinikum · DEMedizinische Hochschule Hannover · DEProf. Hess Kinderklinik · DESt Clement's Hospital · GBSt. Josef-Hospital · DESt Mary's Hospital · JPUniversity Hospital Ulm · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundJuvenile dermatomyositis (JDM) is the most common inflammatory myopathy in childhood and a major cause of morbidity among children with pediatric rheumatic diseases. The management of JDM is very heterogeneous. The JDM working group of the Society for Pediatric Rheumatology (GKJR) aims to define consensus- and practice-based strategies in order to harmonize diagnosis, treatment and monitoring of JDM.

methodsThe JDM working group was established in 2015 consisting of 23 pediatric rheumatologists, pediatric neurologists and dermatologists with expertise in the management of JDM. Current practice patterns of management in JDM had previously been identified via an online survey among pediatric rheumatologists and neurologists. Using a consensus process consisting of online surveys and a face-to-face consensus conference statements were defined regarding the diagnosis, treatment and monitoring of JDM. During the conference consensus was achieved via nominal group technique. Voting took place using an electronic audience response system, and at least 80% consensus was required for individual statements.

resultsOverall 10 individual statements were developed, finally reaching a consensus of 92 to 100% regarding (1) establishing a diagnosis, (2) case definitions for the application of the strategies (moderate and severe JDM), (3) initial diagnostic testing, (4) monitoring and documentation, (5) treatment targets within the context of a treat-to-target strategy, (6) supportive therapies, (7) explicit definition of a treat-to-target strategy, (8) various glucocorticoid regimens, including intermittent intravenous methylprednisolone pulse and high-dose oral glucocorticoid therapies with tapering, (9) initial glucocorticoid-sparing therapy and (10) management of refractory disease.

conclusionUsing a consensus process among JDM experts, statements regarding the management of JDM were defined. These statements and the strategies aid in the management of patients with moderate and severe JDM.

Indexed as

DermatomyositisAntirheumatic AgentsAustriaChildDisease ManagementGermanyGlucocorticoidsHumansSurveys and QuestionnairesAntirheumatic AgentsGlucocorticoidsAntirheumatic agentsChildComparative effectiveness researchConsensusDermatomyositisDiagnosis

Identifiers

PMID29940960
PMCPMC6019723
OpenAlexW2810460332

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.