ArticleAddictive behaviors2018
Prescription tranquilizer/sedative misuse prevalence and correlates across age cohorts in the US.
Article in Addictive behaviors, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
44 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Systematic review of the use of prescription and non-prescription psychotropic drugs and their relation with mental health in university population.Frontiers in psychology · 2025Pooled it
- The epidemiology of benzodiazepine misuse: A systematic review.Drug and alcohol dependence · 2019Pooled it
- Latent Classes of Nonmedical Prescription Tranquilizer Use Motives in US Adolescents and Young Adults.Substance use & addiction journal · 2026Article
- Clinical Characteristics and Treatment Outcomes of Alcohol Withdrawal Syndrome in Adolescents and Young Adults.JAACAP open · 2025Article
- Nationwide trends in diagnosed sedative, hypnotic or anxiolytic use disorders in adolescents and young adults enrolled in Medicaid: 2001-2019.Addiction (Abingdon, England) · 2025Article
- Benzodiazepine Utilization in Ischemic Stroke Survivors: Analyzing Initial Excess Supply and Longitudinal Trends.Stroke · 2024Article
- Characteristics of high-dose benzodiazepine use: nationwide cohort study on new benzodiazepine users with 5-year follow-up.BJPsych open · 2024Article
- Changing patterns of hospitalization for sedative misuse among youth aged 10-24 years in Quebec, Canada.Drug and alcohol dependence reports · 2024Article
- Prevalence and Treatment of Substance Misuse in Older Adults: Beyond Early Adulthood.Substance abuse and rehabilitation · 2024Review
- Stimulant Use Associated With Psychosocial Factors, HIV Risk, and Concurrent Hazardous Alcohol Use Among US Adults: Exploratory Cross-Sectional Questionnaire Study.JMIR formative research · 2023Article
- Severity of behavioral addiction symptoms among young adults using non-prescribed sedatives/hypnotics.Addictive behaviors reports · 2023Article
- Use of Daridorexant among Patients with Chronic Insomnia: A Retrospective Observational Analysis.Journal of clinical medicine · 2023Article
- [Appropriate Use and Abuse of Sedative-Hypnotic Drugs].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2023Review
- Prevalence and correlates of the misuse of z-drugs and benzodiazepines in the National Survey on Drug Use and Health.Frontiers in psychiatry · 2023Article
- Prescription Psychotherapeutic Drug Use and Nicotine Use among Young People in the United States.Substance use & misuse · 2023Article
- Prescription drug dependence with and without concurrent illicit drug use: a multicenter cross-sectional survey among an addiction treatment seeking population.Frontiers in psychiatry · 2023Article
- Self-Administration of Fentanyl-Alprazolam Combinations by Rhesus Monkeys Responding under a Progressive-Ratio Schedule.The Journal of pharmacology and experimental therapeutics · 2022Article
- Misuse of prescribed psychotropic medication and drug crime offending: A follow-up case-control study of former adolescent psychiatric inpatients.Criminal behaviour and mental health : CBMH · 2022Article
- Factors associated with non-medical use of prescription drugs among individuals with a legitimate prescription for medical purposes: A population-based study.Nordisk alkohol- & narkotikatidskrift : NAT · 2022Article
- Within-Person Predictors of Same-Day Alcohol and Nonmedical Prescription Drug Use Among Youth Presenting to an Urban Emergency Department.Journal of studies on alcohol and drugs · 2022Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
backgroundPrescription tranquilizer/sedative (e.g., alprazolam, zolpidem) misuse (i.e., use in ways not intended by the prescriber or without a prescription) is understudied, with little research identifying misuse correlates. Identification of key correlates could identify subgroups more likely to engage in misuse, allowing for targeted treatment. This work examines tranquilizer/sedative use and misuse prevalence rates and misuse correlates across U.S. age cohorts, using nationally representative data.
methodsData were from the 2015-16 National Survey on Drug Use and Health (n = 114,043). Analyses used design-based logistic regression for past-year tranquilizer/sedative misuse correlates across participants or those engaged in past-year use; past-month misuse correlates were also examined in those with past-year misuse.
resultsYoung adults (18-25 years) had the highest prevalence of past-year and past-month tranquilizer/sedative misuse, with 42.8% of those with past-year use also engaged in misuse. Mental health correlates were associated with past-year misuse, while substance use, particularly opioid misuse, was associated with both past-year and past-month misuse. Substance use correlate strength was most likely to vary by age group, with older adults (65 years and older) having fewer significant correlates overall.
conclusionsThis work highlighted young adults and those with other substance use as most likely to engage in tranquilizer/sedative misuse. In particular, those endorsing suicidality and reporting opioid misuse are a subgroup of concern, given their especially elevated rates of misuse and the increased risk for overdose imparted by tranquilizer/sedative medication. Workplace-based interventions for young adults and school-based universal prevention may be warranted to limit tranquilizer/sedative misuse in these groups.
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