Evidence map›Paper›PMID 29940042›Full record

ArticlePLoS neglected tropical diseases2018

Low prevalence of HTLV1/2 infection in a population of immigrants living in southern Italy.

Loredana Alessio, Carmine Minichini, Mario Starace, Laura Occhiello, Mara Caroprese, Giovanni Di Caprio, Caterina Sagnelli, Luciano Gualdieri, Mariantonietta Pisaturo, Lorenzo Onorato and 5 more

Open access · goldAbstract read
In one paragraph

Article in PLoS neglected tropical diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Estimates of Cancer Mortality Attributable to Carcinogenic Infections in Italy.International journal of environmental research and public health · 2020
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Loredana AlessioInfectious Diseases Unit, AORN Sant' Anna and San Sebastiano, Caserta, Italy.
Carmine MinichiniDepartment of Mental Health and Public Medicine, Section of Infectious Diseases, University of Campania Luigi Vanvitelli, Naples, Italy.
Mario StaraceDepartment of Mental Health and Public Medicine, Section of Infectious Diseases, University of Campania Luigi Vanvitelli, Naples, Italy.
Laura OcchielloDepartment of Mental Health and Public Medicine, Section of Infectious Diseases, University of Campania Luigi Vanvitelli, Naples, Italy.
Mara CaropreseMedical Center, Centro Sociale ex Canapificio, Caserta, Italy.
Giovanni Di CaprioMedical Center, Centro Sociale ex Canapificio, Caserta, Italy.
Caterina SagnelliMedical Center, Centro Sociale ex Canapificio, Caserta, Italy.
Luciano GualdieriMedical Center, Centro per la Tutela della Salute degli Immigrati, Naples, Italy.
Mariantonietta PisaturoMedical Center, Centro Sociale ex Canapificio, Caserta, Italy.
Lorenzo OnoratoMedical Center, Centro Sociale ex Canapificio, Caserta, Italy.
Gaetano ScottoInfectious Diseases Unit, Foggia, Italy.
Margherita MaceraMedical Center, Centro Sociale ex Canapificio, Caserta, Italy.
Stefania De PascalisDepartment of Mental Health and Public Medicine, Section of Infectious Diseases, University of Campania Luigi Vanvitelli, Naples, Italy.
Evangelista SagnelliDepartment of Mental Health and Public Medicine, Section of Infectious Diseases, University of Campania Luigi Vanvitelli, Naples, Italy.
Nicola CoppolaInfectious Diseases Unit, AORN Sant' Anna and San Sebastiano, Caserta, Italy.ORCID 0000-0001-5897-4949
University of Campania "Luigi Vanvitelli" · ITOspedale Sant'Anna · ITUniversity of Foggia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsTo assess the prevalence of HTLV-1 and HTLV-2 infections in a cohort of immigrants living in southern Italy.

findingsWe screened for antibody to HTLV-1/2 infection 1,498 consecutive immigrants born in endemic areas (sub-Saharan Africa or southern-Asia) by a commercial chemiluminescent microparticle immunoassay. If confirmed in a Western blot assay, which differentiates anti-HTLV-1 from anti-HTLV-2, the positive sera were tested for specific HTLV RNA by a home-made PCR. The immigrants investigated were more frequently males (89.05%), young (median age 26 years), with a low level of education (median schooling 6 years), born in sub-Saharan Africa (79.70%). They had been living in Italy for a median period of 5 months. Only one (0.07%) subject was anti-HTLV-1 -positive/HTLV-1 RNA-negative; he was an asymptomatic 27-year-old male from Nigeria with 6 years' schooling who stated unsafe sexual habits and unsafe injection therapy.

conclusionsThe data suggest screening for HTLV1 and HTLV-2 infections all blood donors to Italy from endemic countries at least on their first donation; however, a cost-effectiveness study is needed to clarify this topic.

Indexed as

AdultEmigrants and ImmigrantsFemaleHTLV-II InfectionsHTLV-I InfectionsHumansHuman T-lymphotropic virus 1Human T-lymphotropic virus 2ItalyMalePrevalence

Identifiers

PMID29940042
PMCPMC6034900
OpenAlexW2809466373

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.