ArticlePloS one2018
Health-related quality of life in intensive care survivors: Associations with social support, comorbidity, and pain interference.
Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04745611 (Neurological and Neuropsychological Sequelae of COVID-19 Infection), which is not on this map. Cited by 18 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neurological and Neuropsychological Sequelae of COVID-19 Infection
Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Comparative effectiveness of non-pharmacological interventions on health-related quality of life in ICU patients: a network meta-analysis.Frontiers in medicine · 2026Pooled it
- Effect of intensive care unit diary on quality of life of intensive care unit survivors and their relatives: A systematic review and meta-analysis.Nursing open · 2023Pooled it
- Depressive symptoms are a key determinant of health-related quality of life in ICU survivors with psychological distress.Scientific reports · 2026Trial
- Distinct Health-Related Quality of Life Recovery Trajectories Among ICU Survivors: A Multicentre Prospective Cohort Study Using the EQ-5D-5L.Nursing in critical care · 2026Observational
- Factors associated with post-traumatic growth in severe COVID-19 patients discharged from intensive care: the influence of near-death experiences.Scientific reports · 2026Article
- Social support and recovery in acute respiratory distress syndrome survivors: a prospective cohort study.ERJ open research · 2025Article
- Hope among patients discharged from an intensive care unit: A prospective cohort study.Nursing in critical care · 2025Article
- Long-Term Quality of Life Among Intensive Care Units Survivors.Risk management and healthcare policy · 2025Article
- Lower quality of life in obese ICU survivors: a multicenter cohort study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024Article
- Factor Impacting Quality of Life Among Sepsis Survivors During and After Hospitalization: A Systematic Review of Current Empirical Evidence.Journal of multidisciplinary healthcare · 2024Review
- Article
- Physical therapy in the intensive care unit: A cross-sectional study of three Asian countries.PloS one · 2023Article
- Characteristics and influence on quality of life of new-onset pain in critical COVID-19 survivors.European journal of pain (London, England) · 2022Article
- Experience of discomfort and its self-management strategies in ICU patients.Journal of family medicine and primary care · 2022Article
- Quality of life of COVID-19 critically ill survivors after ICU discharge: 90 days follow-up.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2021Article
- Pain interference and quality of life in combat veterans: Examining the roles of posttraumatic stress disorder, traumatic brain injury, and sleep quality.Rehabilitation psychology · 2021Article
- Chronic pain in critical care survivors: a narrative review.British journal of anaesthesia · 2019Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundExperiences during a stay in the intensive care unit (ICU), including pain, delirium, physical deterioration, and the critical illness itself, may all influence survivors' health-related quality of life (HRQOL). However, few studies have examined the influence of social support, comorbidity, and pain interference on ICU survivors' HRQOL.
objectivesTo investigate possible associations between social support, number of comorbidities, and pain interference on HRQOL in ICU survivors.
methodsICU survivors responded to a survey 3 months (n = 118) and 1 year (n = 89) after ICU discharge. HRQOL was measured using the Short Form Health Survey-12 (v1), social support using the revised Social Provision Scale, pain interference using the Brief Pain Inventory-Short Form, and comorbidities using the Self-Administered Comorbidity Questionnaire.
resultsPhysical and mental HRQOL were reduced at both 3 months and 1 year in ICU survivors compared with the general population. This reduction was more pronounced at 3 months for physical HRQOL, while a small reduction in mental HRQOL was not clinically relevant. Social support was statistical significantly positively associated with mental HRQOL at 3 months, while number of comorbidities was statistical significantly associated with a reduction in physical HRQOL at 3 months and 1 year and mental HRQOL at 1 year. Lastly pain interference was significantly associated with a reduction in physical HRQOL at 3 months and 1 year.
conclusionsICU survivors primarily report reduced physical HRQOL. Social support was positively associated with mental HRQOL, while number of comorbidities, and pain interference were all significantly associated with a reduction in HRQOL. Pain interference was associated with the largest reduction in HRQOL.
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