ArticlePloS one2018
Association of cerebral oxygenation with estimated glomerular filtration rate and cognitive function in chronic kidney disease patients without dialysis therapy.
Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Steady-state regional cerebral oxygen saturation integrates multidimensional periprocedural factors and predicts long-term mortality after transcatheter aortic valve implantation.Journal of anesthesia · 2026Article
- Structural brain changes, cerebral oxygenation, and cognitive function in hemodialysis patients: a cross-sectional study.Frontiers in medicine · 2026Article
- Cerebral Haemodynamics and Cognitive Impairment in Chronic Haemodialysis Patients: A Pilot Study.Journal of clinical medicine · 2025Article
- Article
- Cognitive impairment in chronic kidney disease: role of brain imaging, functional imaging, electroencephalography, cerebrospinal fluid biomarkers and sensors.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2025Review
- Differences of cerebral oxygen saturation in dialysis patients: a comparison of three principals of near infrared spectroscopy.Journal of anesthesia · 2023Article
- Quantification of Epistemic Capacity and Physical Frailty in Chronic Kidney Disease: Koch's Disease Co-infection.Cureus · 2023Article
- Effects of percutaneous transluminal angioplasty and associated factors in access hand oxygenation in patients undergoing hemodialysis.Scientific reports · 2023Article
- Estimated glomerular filtration rate is a biomarker of cognitive impairment in Parkinson's disease.Frontiers in aging neuroscience · 2023Article
- Cerebral oxygenation and body mass index association with cognitive function in chronic kidney disease patients without dialysis: a longitudinal study.Scientific reports · 2022Article
- Article
- The effect of high-flow arteriovenous fistulas on systemic haemodynamics and brain oxygenation.ESC heart failure · 2021Article
- Interactions Between Kidney Function and Cerebrovascular Disease: Vessel Pathology That Fires Together Wires Together.Frontiers in neurology · 2021Review
- Decrease in hand and cerebral oxygenation after percutaneous transluminal angioplasty for arteriovenous fistula stenosis in a patient on chronic hemodialysis.Radiology case reports · 2020Article
- Continuous monitoring of changes in cerebral oxygenation during hemodialysis in a patient with acute congestive heart failure.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2020Article
- Impaired Frontal Brain Activity in Patients With Heart Failure Assessed by Near-Infrared Spectroscopy.Journal of the American Heart Association · 2020Article
- Associations of cerebral oxygenation with hemoglobin levels evaluated by near-infrared spectroscopy in hemodialysis patients.PloS one · 2020Article
- Diagnostic and prognostic values of cerebral oxygen saturations measured by INVOS™ in patients with ischemic and hemorrhagic cerebrovascular disease.Turkish journal of emergency medicine · 2019Article
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13 authors.
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Abstract
backgroundA decline in estimated glomerular filtration rate (eGFR) is reportedly associated with increased prevalence rates of cognitive impairment. However, data concerning the association between the cerebral saturation of oxygen (rSO2) and cognitive function of patients with chronic kidney disease (CKD) is limited. This study aimed to (i) elucidate the clinical factors associating with cerebral rSO2 and (ii) investigate the association between cerebral rSO2 and cognitive assessment in CKD patients.
methodsA total of 40 CKD patients not requiring dialysis (26 men and 14 women; mean age, 61.0 ± 2.7 years) were recruited. The numbers of patients at each CKD stage were as follows: G1, 5; G2, 8; G3a, 6; G3b, 5; G4, 11; and G5, 5. Cerebral rSO2 was monitored at the forehead using the oxygen saturation monitor INVOS 5100C. The cognitive function of each patient was confirmed using the Mini-Mental State Examination (MMSE).
resultsCerebral rSO2 levels were significantly higher in CKD patients than in hemodialysis patients (63.8 ± 1.5% vs. 44.9 ± 2.2%, p < 0.001). Multiple regression analysis showed that cerebral rSO2 was independently associated with eGFR (standardized coefficient: 0.530), serum albumin concentration (standardized coefficient: 0.365), and serum sodium concentration (standardized coefficient: 0.224). Furthermore, MMSE showed a significantly positive correlation with cerebral rSO2 (r = 0.624, p < 0.001).
conclusionsCerebral rSO2 was affected by eGFR and serum albumin and sodium concentrations in CKD patients. Furthermore, cerebral rSO2 monitoring, which reflected MMSE scores, might be a useful method for assessing cognitive function in CKD patients.
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