ArticlePloS one2018
Trends in corneal transplantation at the University Eye Hospital in Tübingen, Germany over the last 12 years: 2004 - 2015.
Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Artificial intelligence for detecting keratoconus.The Cochrane database of systematic reviews · 2023Pooled it
- [Knowledge and attitudes towards corneal donation among medical students].Die Ophthalmologie · 2026Article
- Changing indications for and trends of keratoplasty in a tertiary comprehensive hospital in northern part of China from 2002 to 2021: a 20-year review.BMC ophthalmology · 2024Article
- Ocular condition prognosis in Keratoconus patients after corneal ring implantation using artificial neural networks.Heliyon · 2023Article
- Advances in artificial intelligence models and algorithms in the field of optometry.Frontiers in cell and developmental biology · 2023Review
- Impact of keratoconus stage on outcome after corneal crosslinking.BMC ophthalmology · 2022Article
- Accuracy of Machine Learning Assisted Detection of Keratoconus: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2022Review
- Indications and techniques of corneal transplants performed in one center in Southern Poland, in the years 2001-2020.PloS one · 2022Article
- Recent indications of endothelial keratoplasty at a tertiary eye care center in South India.International ophthalmology · 2021Article
- Changing Indications for Penetrating Keratoplasty in Bahrain in a Tertiary Referral Centre.Clinical ophthalmology (Auckland, N.Z.) · 2021Article
- Extracellular matrix changes in corneal opacification vary depending on etiology.Molecular vision · 2021Article
- Corneae from body donors in anatomy department: valuable use for clinical transplantation and experimental research.BMC ophthalmology · 2020Article
- [Long-term experiences with corneal crosslinking in patients with progressive keratoconus at the University Eye Hospital in Tübingen, Germany].Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft · 2020Observational
- Evaluating the Performance of Various Machine Learning Algorithms to Detect Subclinical Keratoconus.Translational vision science & technology · 2020Article
- Fuchs endothelial corneal dystrophy and corneal endothelial diseases: East meets West.Eye (London, England) · 2020Review
- A 5-year analysis of endothelialInternational journal of ophthalmology · 2020Article
- Changing trends in penetrating keratoplasty indications at a tertiary eye care center in Budapest, Hungary between 2006 and 2017.International journal of ophthalmology · 2020Article
- A 27-Year Report from the Central Eye Bank of Iran.Journal of ophthalmic & vision researchReview
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study aimed to investigate the trends in the surgical methods and leading indications for corneal transplantations carried out over the last 12 years.
methodsThe data from the corneal graft waiting list and from all keratoplasties carried out between 2004 and 2015 at the University Eye Hospital in Tübingen were retrospectively analyzed.
resultsA total of 1,185 keratoplasties were performed between 2004 and 2015 at this hospital. The most common surgical indications for corneal transplantation were Fuchs' endothelial corneal dystrophy (35.2%) and keratoconus (18.9%) with keratoconus being the leading cause during early years (from 2004 to 2009) and Fuch's dystrophy being the leading cause from 2010 to 2015. Overall, the total count of performed keratoplasties increased, from 385 corneal transplantations during the first 6-year period to 800 corneal transplantations during the second 6-year period (P = 0.008, using Mann-Whitney test). The Descemet's membrane endothelial keratoplasty has become the favored surgical method for endothelial disorders with the number of Descemet's membrane endothelial keratoplasties increasing significantly from 2008 to 2015. This increasing trend was statistically significant (P < 0.001 using multivariate adaptive regression splines (MARS). A decreasing trend was also noted for the rate of penetrating keratoplasty since 2008 (P < 0.001 using MARS).
conclusionsThis research showed major changes in the preferred corneal transplantation techniques and leading indications for keratoplasty over the last 12 years. More importantly, it seems that the rapid development and implementation of endothelial keratoplasty, especially the Descemet's membrane endothelial keratoplasty, has had a profound effect on and begun a new era in corneal transplantation.
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