Evidence map›Paper›PMID 29939482›Full record

ArticleAngewandte Chemie (International ed. in English)2018

A Platinum(II) Complex of Heptamethine Cyanine for Photoenhanced Cytotoxicity and Cellular Imaging in Near-IR Light.

Koushambi Mitra, Charles E Lyons, Matthew C T Hartman

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
5.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 96 citations in OpenAlex.

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  20. Photo-controlled delivery of a potent analogue of doxorubicin.Chemical communications (Cambridge, England) · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Koushambi MitraDepartment of Chemistry, Virginia Commonwealth University, 1001 West Main Street, P. O. Box 842006, Richmond, VA, 23284, USA.
Charles E LyonsMassey Cancer Center, Virginia Commonwealth University, 401 College Street, Richmond, VA, 23298, USA.
Matthew C T HartmanDepartment of Chemistry, Virginia Commonwealth University, 1001 West Main Street, P. O. Box 842006, Richmond, VA, 23284, USA.ORCID 0000-0003-0210-1422
Virginia Commonwealth University · US

Funding

Virus Vector Shared ResourceP30CA016059 · NCI · VIRGINIA COMMONWEALTH UNIVERSITY · PI Keri R Maher · 1985 to 2026
$51.0M
NCI NIH HHS P30 CA016059
6 · The paper itself

Abstract

Controlled generation of cytotoxic agents with near-IR light is a current focus of photoactivated cancer therapy, including that involving cytotoxic platinum species. A heptamethine cyanine scaffolded Pt

Indexed as

Antineoplastic AgentsCarbocyaninesCell Line, TumorCell ProliferationCell SurvivalDensity Functional TheoryDrug Screening Assays, AntitumorHumansInfrared RaysMCF-7 CellsMolecular StructureOrganoplatinum CompoundsPhotochemical ProcessesPhotochemotherapyPlatinumAntineoplastic AgentsCarbocyaninesOrganoplatinum CompoundsPlatinumcancercyaninesimaging agentsphotodynamic therapyplatinum

Identifiers

PMID29939482
PMCPMC6548462
OpenAlexW2810558060

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.