Evidence map›Paper›PMID 29939055›Full record

Trial reportJournal of consulting and clinical psychology2018

Measuring fear change within exposures: Functionally-defined habituation predicts outcome in three randomized controlled trials for pediatric OCD.

Kristen G Benito, Jason Machan, Jennifer B Freeman, Abbe M Garcia, Michael Walther, Hannah Frank, Brianna Wellen, Elyse Stewart, Julie Edmunds, Joshua Kemp and 2 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of consulting and clinical psychology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  14. Mechanisms of Change in Exposure Therapy for Anxiety and Related Disorders: A Research Agenda.Clinical psychological science : a journal of the Association for Psychological Science · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Kristen G BenitoDepartment of Psychiatry and Human Behavior, Warren Alpert Medical School of Brown University.
Jason MachanLifespan Biostatistics Core, Lifespan Hospitals.
Jennifer B FreemanDepartment of Psychiatry and Human Behavior, Warren Alpert Medical School of Brown University.
Abbe M GarciaDepartment of Psychiatry and Human Behavior, Warren Alpert Medical School of Brown University.
Michael WaltherDepartment of Psychiatry and Human Behavior, Warren Alpert Medical School of Brown University.
Hannah FrankDepartment of Psychology, Temple University.ORCID 0000-0003-2396-4585
Brianna WellenDepartment of Psychology, University of Utah.
Elyse StewartDepartment of Psychology, State University of New York at Binghamton.
Julie EdmundsMassachusetts General Hospital, Harvard Medical School.
Joshua KempDepartment of Psychiatry and Human Behavior, Warren Alpert Medical School of Brown University.
Jeffrey SapytaDepartment of Psychiatry and Behavioral Sciences, Duke University Medical School.
Martin FranklinPerelman School of Medicine, University of Pennsylvania.

Funding

Quality Assessment in Exposure TherapyR01MH112516 · NIMH · EMMA PENDLETON BRADLEY HOSPITAL · PI BENITO, KRISTEN G · 2017 to 2021
$1.7M
CBT for Pediatric OCD: Effective Therapist Behaviors and Community Training PilotR33MH096828 · NIMH · RHODE ISLAND HOSPITAL · PI BENITO, KRISTEN G, FREEMAN, JENNIFER B · 2014 to 2016
$937k
CBT for Pediatric OCD: Effective Therapist Behaviors and Community Training PilotR21MH096828 · NIMH · RHODE ISLAND HOSPITAL · PI BENITO, KRISTEN G, FREEMAN, JENNIFER B · 2012 to 2013
$437k
NIMH NIH HHS R01 MH112516NIMH NIH HHS R21 MH096828NIMH NIH HHS R33 MH096828
6 · The paper itself

Abstract

objectiveThis study measured a variety of within-exposure fear changes and tested the relationship of each with treatment outcomes in exposure therapy.

methodWe coded 459 videotaped exposure tasks from 111 participants in 3 clinical trials for pediatric obsessive-compulsive disorder (OCD; POTS trials). Within exposures, fear level was observed continuously and alongside exposure process. Fear change metrics of interest were selected for relevance to mechanistic theory. Fear decreases were classified by function; nonhabituation decreases were associated with observed nonlearning processes (e.g., avoidance), whereas habituation decreases appeared to result from an internal and indirect process. Outcomes were posttreatment change in symptom severity, global improvement, and treatment response.

resultsGreater cumulative habituation across treatment was associated with larger reductions in symptom severity, greater global improvement, and increased odds of treatment response. Fear activation, fear variability, and nonhabituation fear decreases did not predict any outcomes. Exploratory analyses examined fear changes during habituation and nonhabituation exposures; higher peak fear during nonhabituation exposures was associated with attenuated global improvement.

conclusionsHabituation is conceptually consistent with multiple mechanistic theories and should continue to be investigated as a practical marker of initial extinction learning and possible moderator of the relationship between fear activation and outcome. Results support the importance of functional and frequent fear measurement during exposures, and discussion considers implications of these findings for future studies aiming to understand learning during exposure and improve exposure delivery. (PsycINFO Database Record

Indexed as

LearningAdolescentChildChild, PreschoolFearFemaleHumansImplosive TherapyMaleObsessive-Compulsive DisorderTreatment Outcome

Identifiers

PMID29939055
PMCPMC6023553

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.