Evidence map›Paper›PMID 29938868›Full record

SynthesisAnnals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc2019

The presence of atrial fibrillation in Takotsubo cardiomyopathy is predictive of mortality: Systematic review and meta-analysis.

Narut Prasitlumkum, Veraprapas Kittipibul, Nath Limpruttidham, Pattara Rattanawong, Pakawat Chongsathidkiet, Thosaporn Boondarikpornpant

Open access · bronzeAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. The presence of atrial fibrillation in Takotsubo cardiomyopathy is predictive of mortality: Systematic review and meta-analysis.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2019
    Pooled it
  2. Incidence of ischemic stroke in Takotsubo cardiomyopathy patients: a systematic review and meta-analysis.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2026
    Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Update of Takotsubo cardiomyopathy: Present experience and outlook for the future.International journal of cardiology. Heart & vasculature · 2022
    Review
  9. Article
  10. Article
  11. Article
  12. Response to letter of the editor "Mortality in Takotsubo Cardiomyopathy should also be accounted based on predisposing etiology".Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2019
    Article
  13. Mortality in Takotsubo cardiomyopathy should also be accounted based on predisposing etiology.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2019
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Narut PrasitlumkumUniversity of Hawaii Internal Medicine Residency Program, Honolulu, Hawaii.ORCID 0000-0002-7956-0574
Veraprapas KittipibulFaculty of Medicine, Department of Medicine, Chulalongkorn University, Bangkok, Thailand.
Nath LimpruttidhamUniversity of Hawaii Internal Medicine Residency Program, Honolulu, Hawaii.
Pattara RattanawongUniversity of Hawaii Internal Medicine Residency Program, Honolulu, Hawaii.ORCID 0000-0001-9419-5854
Pakawat ChongsathidkietDepartment of Pathology, Duke University Medical Center, Durham, North Carolina.
Thosaporn BoondarikpornpantFaculty of Medicine, Department of Medicine, Chulalongkorn University, Bangkok, Thailand.
University of Hawaii System · USChulalongkorn University · THDuke Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAtrial fibrillation (AF) is known as the most common arrhythmia and an independent risk factor for mortality. Recent studies suggest that AF is associated with morbidity and mortality in Takotsubo cardiomyopathy (TTC). However, a systematic review and meta-analysis of the literature have not been done. We assessed the association between AF in patients with TTC and mortality by a systematic review of the literature and a meta-analysis.

methodsWe comprehensively searched the databases of MEDLINE and EMBASE from inception to January 2018. Included studies were published prospective or retrospective cohort studies that compared all-cause mortality in TTC with AF versus without AF. Data from each study were combined using the random-effects, generic inverse variance method of DerSimonian and Laird to calculate risk ratios and 95% confidence intervals.

resultsFive studies from August 2008 to October 2017 were included in this meta-analysis involving 2,321 subjects with TTC (243 with AF and 2,078 without AF). The presence of AF was associated with all-cause mortality (pooled odds ratio = 2.19, 95% confidence interval: 1.57-3.06, p < 0.001, I

conclusionAtrial fibrillation increased all-cause mortality by double among patients with TTC compared to without it. Our study suggests that the presence of AF in TTC is prognostic for all-cause mortality.

Indexed as

Cause of DeathAtrial FibrillationComorbidityElectrocardiographyFemaleHumansMalePrevalenceProspective StudiesRetrospective StudiesRisk AssessmentSurvival AnalysisTakotsubo Cardiomyopathyatrial fibrillationmortalityTakotsubo cardiomyopathy

Identifiers

PMID29938868
PMCPMC6931621
OpenAlexW2811098273

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.