ArticleAnnals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc2018
Association of QRS-T angle and heart rate variability with major cardiac events and mortality in hemodialysis patients.
Article in Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Placebo Analgesia, Nocebo Hyperalgesia, and the Cardiovascular System: A Qualitative Systematic Review.Frontiers in physiology · 2020Pooled it
- Direct evaluation of the electrocardiographic spatial QRS-T angle without the need for orthogonal transformation.Scientific reports · 2026Article
- Association of serum resolvin D1 with the risk of major adverse cardiovascular events in hemodialysis patients.International urology and nephrology · 2025Article
- Mental fatigue impairs endurance performance in a time-to-exhaustion handgrip task: psychophysiological markers of effort engagement dynamics.Frontiers in psychology · 2025Article
- The Clinical Significance and Application of Heart Rate Variability in Dialysis Patients: A Narrative Review.Biomedicines · 2024Review
- Evaluation of the Cardiac Conduction System in Fibromyalgia Patients With Complaints of Palpitations.Cureus · 2022Article
- Diabetes without Overt Cardiac Disease Is Associated with Markers of Abnormal Repolarization: A Case-Control Study.Life (Basel, Switzerland) · 2022Article
- Long- and short-term fluctuations compared for several organ systems across sleep stages.Frontiers in network physiology · 2022Article
- Heat Shock Protein 27 Levels Predict Myocardial Inhomogeneities in Hemodialysis Patients.Mediators of inflammation · 2022Article
- Intra-subject stability of different expressions of spatial QRS-T angle and their relationship to heart rate.Frontiers in physiology · 2022Article
- Effects of interdialytic interval on heart rate variability in chronic hemodialysis patients: a cross-sectional study.Scientific reports · 2021Article
- T-wave morphology descriptors in patients with bulimia nervosa.Eating and weight disorders : EWD · 2021Article
- A Serious Game to Improve Emotion Regulation in Treatment-Seeking Individuals With Gambling Disorder: A Usability Study.Frontiers in psychology · 2021Article
- Positive Relationship Between Precompetitive Sympathetic Predominance and Competitive Performance in Elite Extreme Sports Athletes.Frontiers in sports and active living · 2021Article
- Connecting cognition, cardiology, and chromosomes: Cognitive reappraisal impacts the relationship between heart rate variability and telomere length in CD8Psychoneuroendocrinology · 2020Article
- The improvement of QRS-T angle as a manifestation of reverse electrical remodeling following renal transplantation in end-stage kidney disease patients on haemodialysis.BMC nephrology · 2019Article
- Hemodialysis Procedure-Associated Autonomic Imbalance and Cardiac Arrhythmias: Insights From Continuous 14-Day ECG Monitoring.Journal of the American Heart Association · 2019Article
- Sudden Cardiac Death in Dialysis: Arrhythmic Mechanisms and the Value of Non-invasive Electrophysiology.Frontiers in physiology · 2019Review
- QRS-T Angle Predicts Cardiac Risk and Correlates With Global Longitudinal Strain in Prevalent Hemodialysis Patients.Frontiers in physiology · 2019Article
- Association of QRS-T angle and heart rate variability with major cardiac events and mortality in hemodialysis patients.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2018Article
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4 authors.
Funding
Abstract
introductionMortality in hemodialysis (HD) patients is high with significant proportion attributed to fatal arrhythmias. In a pilot study, we showed that intradialytic electrocardiographic (ECG) monitoring can yield stable profiles of selected repolarisation descriptors and heart rate variability (HRV) parameters. This study investigated the relationship of these ECG markers with major adverse cardiac events (MACE) and mortality.
methodsContinuous ECGs were obtained during HD and repeated five times at 2-week intervals. The QRS-T angle calculated as Total Cosine R to T (TCRT) and T-wave morphology dispersion (TMD) were calculated in overlapping 10 s ECG segments. High- (HF) and low (LF)-frequency components and the LF/HF ratio of HRV were calculated every 5 min. These indices were averaged during the first hour of dialysis and subsequently overall recordings in each subject.
resultsAll ECG parameters were available in 72 patients aged 61 ± 15, 23 (31.9%) females and 26 (36.1%) diabetics. After a median follow up of 54.8 months, 16 patients died, 20 were transplanted, and 9 suffered MACE. TCRT (in degrees) was higher and LF/HF was lower in patients who died compared to survivors (112 ± 30 vs. 73 ± 35, p = 0.000 and 0.222 ± 0.418 vs. 0.401 ± 0.274, p = 0.000, respectively) and in MACE positive compared to negative (117 ± 40 vs. 77 ± 34, p = 0.017 and 0.125 ± 0.333 vs.0.401 ± 0.274, p = 0.007 respectively). In multivariate Cox regression analysis of mortality risk adjusted for age, diabetes mellitus, and coronary artery disease, TCRT and LF/HF remained significant predictors (p < 0.05).
conclusionQRS-T angle and HRV may serve risk assessment in future prospective studies in HD patients.
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