Evidence map›Paper›PMID 29938794›Full record

ArticleThe Journal of physiology2018

Age-related changes in cardiac electrophysiology and calcium handling in response to sympathetic nerve stimulation.

Samantha D Francis Stuart, Lianguo Wang, William R Woodard, G Andre Ng, Beth A Habecker, Crystal M Ripplinger

Open access · greenAbstract read
In one paragraph

Article in The Journal of physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 46 citations in OpenAlex.

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  8. Guidelines for assessment of cardiac electrophysiology and arrhythmias in small animals.American journal of physiology. Heart and circulatory physiology · 2022
    Review
  9. [A case of portal vein recanalization and symptomatic heart failure].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2022
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Samantha D Francis StuartDepartment of Pharmacology, University of California Davis, Davis, CA, USA.ORCID 0000-0002-7462-8912
Lianguo WangDepartment of Pharmacology, University of California Davis, Davis, CA, USA.ORCID 0000-0002-4747-0419
William R WoodardDepartment of Physiology and Pharmacology, Oregon Health and Science University, Portland, OR, USA.
G Andre NgDepartment of Cardiovascular Sciences, University of Leicester, NIHR Leicester Biomedical Research Centre, Leicester, UK.ORCID 0000-0001-5965-0671
Beth A HabeckerDepartment of Physiology and Pharmacology, Oregon Health and Science University, Portland, OR, USA.ORCID 0000-0002-4658-8730
Crystal M RipplingerDepartment of Pharmacology, University of California Davis, Davis, CA, USA.ORCID 0000-0002-9908-4106
University of California, Davis · USOregon Health & Science University · USUniversity of Leicester · GB

Funding

Neurotrophins and post-infarct plasticity in cardiac sympathetic neuronsR01HL093056 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI BETH A HABECKER · 2009 to 2026
$7.9M
The Role of Adrenergic Stimulation in ArrhythmogenesisR01HL111600 · NHLBI · UNIVERSITY OF CALIFORNIA-IRVINE · PI Crystal May Ripplinger · 2012 to 2026
$7.1M
Predoctoral Training in Pharmacological SciencesT32GM099608 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI HELL, JOHANNES W · 2012 to 2021
$2.2M
British Heart Foundation RG/17/3/32774NHLBI NIH HHS R01 HL093056NHLBI NIH HHS R01 HL111600NIGMS NIH HHS T32 GM099608
6 · The paper itself

Abstract

key pointsAgeing results in changes to cardiac electrophysiology, Ca ABSTRACT: The objective of this study was to determine how age-related changes in sympathetic structure and function impact cardiac electrophysiology and intracellular Ca

Indexed as

Electric StimulationSympathetic Nervous SystemAction PotentialsAdrenergic beta-AgonistsAnimalsArrhythmias, CardiacCalciumElectrophysiologyFemaleFibrosisHeart RateIsoproterenolMiceMice, Inbred C57BLMyocytes, CardiacReceptors, Adrenergic, betaAdrenergic beta-AgonistsCalciumIsoproterenolReceptors, Adrenergic, betaadrenergicagingarrhythmiasympathetic

Identifiers

PMID29938794
PMCPMC6117583
OpenAlexW2891325487

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.