Evidence map›Paper›PMID 29938451›Full record

ArticleAsian Pacific journal of cancer prevention : APJCP2018

Assessment of Depression and Anxiety in Breast Cancer Patients: Prevalence and Associated Factors

Konstantinos Tsaras, Ioanna V Papathanasiou, Dimitra Mitsi, Aikaterini Veneti, Martha Kelesi, Sofia Zyga, Evangelos C Fradelos

Registry-linked trialAbstract read
In one paragraph

Article in Asian Pacific journal of cancer prevention : APJCP, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05732064 (Effects of Low-dose Dexmedetomidine-esketamine Combined Nasal Administration at Night on Perioperative Sleep Quality in Breast Cancer Patients), which is not on this map. Cited by 219 papers, 13 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
219citing papers in PubMed, 13 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05732064 phase4completednot on this mapstarted 2023, after this paper: background citation

Effects of Low-dose Dexmedetomidine-esketamine Combined Nasal Administration at Night on Perioperative Sleep Quality in Breast Cancer Patients: a Randomized, Double-blind, Placebo-controlled Trial

TypeinterventionalSponsorPeking University First HospitalRan2023 to 2025Enrolled180ConditionsBreast Cancer, Perioperative Period, Dexmedetomidine, EsketamineArmsDexmedetomidine, Esketamine, Normal saline
3 · Its place in the literature

Who cites it

219 citing papers in PubMed, 13 syntheses or guidelines pooled it.

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  8. Psychological interventions for women with non-metastatic breast cancer.The Cochrane database of systematic reviews · 2023
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  11. The prevalence of depression and anxiety in patients with cancer in Iran: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
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159 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Konstantinos TsarasDepartment of Nursing, Technological Educational Institute of Thessaly, Larissa, Greece. Email: ktsa@teilar.gr
Ioanna V Papathanasiou
Dimitra Mitsi
Aikaterini Veneti
Martha Kelesi
Sofia Zyga
Evangelos C Fradelos

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Having breast cancer or receiving treatment has been seen as a traumatic experience for women due to its impacts on their self-image and sexual relationship, and may lead to an psychological reactions such as denial, anger, or intense fear toward their disease and treatment process. Also many of breast cancer patients have psychiatric morbidities such as depression and anxiety. Purpose: The purpose of this study was to assess the prevalence and associated factors of depression and anxiety in breast cancer patients, in order to identify independent predictors of mental health disorders risk. Material and Methods: A cohort of 152 breast cancer patients who were attending an outpatient oncology department was recruited. Data were collected with a structured questionnaire consisted by social, clinical and demographic information and PHQ-2 and GAD-2 scales. Results: The mean age of the patients was 53.25 years (SD=12.10), 69.7% of the patients underwent mastectomy and 30.3% ongectomy. Chemotherapy received 46.1% of patients as adjuvant therapy, 15.8% radiotherapy and 38.2% received both chemotherapy and radiotherapy. A large percentage found to be classified as depressed (38.2%) and anxious (32.2%) and factors that found to be associated were age, marital status, educational level, stage of cancer from univariate analyses and place of residence, religion, symptoms burden from multivariate analysis (for depression and anxiety). Conclusions: Breast cancer patients are in high risk for developing psychiatric disorders such as depression and anxiety. Being rural resident, non-Orthodox Christian and experiencing extend symptom burden can be predicting factors associated with depression and anxiety in breast cancer patients.

Indexed as

Stress, PsychologicalAdultAgedAnxiety DisordersBreast NeoplasmsCohort StudiesCombined Modality TherapyCross-Sectional StudiesDepressive DisorderFemaleFollow-Up StudiesGreeceHumansMiddle AgedPrevalencePrognosisanxietybreast cancerdepressionpredictorsPsychological distress

Identifiers

PMID29938451
PMCPMC6103579

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.