Observational studySupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2019
Nutritional status in patients with head and neck cancer undergoing radiotherapy: a longitudinal study.
Observational study in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
43 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Malnutrition and radiation therapy in head and neck cancers, a systematic review on reported definitions and associated factors.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Pooled it
- The changing face of head and neck cancer: are patients with human papillomavirus-positive disease at greater nutritional risk? A systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022Pooled it
- Effects of nutritional support on the clinical outcomes of well-nourished patients with cancer: a meta-analysis.European journal of clinical nutrition · 2020Pooled it
- Pembrolizumab combined with nab-paclitaxel and platinum in recurrent/metastatic HNSCC: efficacy, safety, and survival predictive model.ESMO open · 2026Trial
- Effect of a Home-Based Exercise Program on Muscle Mass, Fatigue, and Health-Related Quality of Life Among Patients with Oral Cancer: A Randomized Trial.Head & neck · 2026Trial
- The Impact of Human Papillomavirus (HPV) Associated Oropharyngeal Squamous Cell Carcinoma (OPSCC) on Nutritional Outcomes.Nutrients · 2021Trial
- Patient-generated subjective global assessment and nutritional risk index for assessing nutritional decline during radical chemoradiotherapy in locally advanced head and neck cancer: a prospective single-center Indian study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Observational
- Timing matters: gastrostomy placement and outcomes in patients with head and neck cancer undergoing chemoradiotherapy.Frontiers in nutrition · 2026Article
- Nutritional Interventions in Head and Neck Cancer Patients Undergoing Chemoradiotherapy: A Systematic Review and Meta-Analysis.Healthcare (Basel, Switzerland) · 2025Review
- Psychological distress of patients with head and neck cancer following various oncologic treatments-A longitudinal study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
- Nutrition in head and neck cancer care: a roadmap and call for research.The Lancet. Oncology · 2025Review
- Exercise and Nutrition Therapy in a Patient With Glottic Cancer Cachexia Undergoing Chemoradiotherapy: A Case Report.Cureus · 2025Article
- Predictive Factors of the Degrees of Malnutrition According to GLIM Criteria in Head and Neck Cancer Patients: Valor Group.Cancers · 2024Article
- Correlation Analysis Between Prognostic Nutritional Index Trajectory Categories and Radiotherapy-induced Severe Oral Mucositis in Head and Neck Cancer Patients Undergoing Radiotherapy.Oral health & preventive dentistry · 2024Observational
- Improving the nutritional evaluation in head neck cancer patients using bioelectrical impedance analysis: Not only the phase angle matters.Journal of cachexia, sarcopenia and muscle · 2024Observational
- Assessment of the Dietary Intake Changes in Patients with Head and Neck Cancer Treated with Radical Radiotherapy.Nutrients · 2024Article
- Effect of nutrition impact symptoms on oral nutritional supplements energy intake and use days in patients with head and neck cancer: A cross-sectional study.Cancer medicine · 2024Article
- Investigating oral somatosensory perception and oral symptoms of head and neck cancer patients: insights on eating behaviour.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Article
- Evidence summary on managing radiotherapy-induced oral mucositis in patients with head and neck cancer.Asia-Pacific journal of oncology nursing · 2024Review
- Oral somatosensory alterations and salivary dysfunction in head and neck cancer patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
purposePatients with head and neck cancers are susceptible to malnutrition during radiotherapy. This study aimed to determine the changes in the nutritional status and its determinants in patients with head and neck cancer during radiotherapy.
methodsThis prospective observational study was performed in an outpatient Radiation Oncology clinic with a sample of 54 patients. An interview form (including anthropometric and laboratory parameters), the Patient-Generated Subjective Global Assessment to assess nutritional status, quality of life scales, and toxicity criteria were used for data collection at the baseline, the end of radiotherapy and 1 and 3 months after radiotherapy.
resultsWhile the majority of the patients (90%) were well nourished at baseline, most of the patients (74%) were malnourished at the end of radiotherapy (p < 0.001). During radiotherapy, patients developed malnutrition, reflected in a decrease in food intake, approximately 5% loss of body weight, a reduction in mid-arm upper circumference and mid-arm muscle mass, and reduced serum protein and albumin levels. The nutritional status was worse in oropharyngeal cancers (p = 0.021), advanced stage (p = 0.004), use of concomitant chemotherapy (p = 0.041), and worse toxicity (p < 0.001). Furthermore, the nutritional status was strongly associated with the quality of life.
conclusionsThis study demonstrated negative impact of radiotherapy on the nutritional status of patients with head and neck cancer. The study also showed the association of the nutritional status and the quality of life. The nutritional status should be assessed during different periods in the trajectory of treatment due to its significant contribution to the quality of life.
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