ReviewCurrent pathobiology reports2018
Intrauterine Inflammation, Epigenetics, and Microbiome Influences on Preterm Infant Health.
Review in Current pathobiology reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 32 citations in OpenAlex.
- Construction of a prediction model for retinopathy of prematurity based on placenta-derived genes and clinical variables.Translational pediatrics · 2026Article
- Guardians of the Gut: Harnessing the Power of Probiotic Microbiota and Their Exopolysaccharides to Mitigate Heavy Metal Toxicity in Human for Better Health.Probiotics and antimicrobial proteins · 2024Review
- DNA methylation in necrotizing enterocolitis.Expert reviews in molecular medicine · 2024Review
- Effects of Sepsis on Immune Response, Microbiome and Oxidative Metabolism in Preterm Infants.Children (Basel, Switzerland) · 2023Review
- Therapeutic Potential of Gut Microbiota and Its Metabolite Short-Chain Fatty Acids in Neonatal Necrotizing Enterocolitis.Life (Basel, Switzerland) · 2023Review
- The First 1000 Days: Assembly of the Neonatal Microbiome and Its Impact on Health Outcomes.Newborn (Clarksville, Md.) · 2022Article
- Chorioamnionitis and neonatal outcomes.Pediatric research · 2022Review
- Prenatal Environmental Metal Exposure and Preterm Birth: A Scoping Review.International journal of environmental research and public health · 2021Article
- Influence of Dietary Components and Traditional Chinese Medicine on Hypertension: A Potential Role for Gut Microbiota.Evidence-based complementary and alternative medicine : eCAM · 2021Review
- From Intrauterine to Extrauterine Life-The Role of Endogenous and Exogenous Factors in the Regulation of the Intestinal Microbiota Community and Gut Maturation in Early Life.Frontiers in nutrition · 2021Review
- Time to regain birth weight predicts neonatal growth velocity: A single-center experience.Clinical nutrition ESPEN · 2020Article
- Preterm infants harbour diverseMicrobial genomics · 2020Article
- Meconium microbiome and its relation to neonatal growth and head circumference catch-up in preterm infants.PloS one · 2020Article
- Differences in Compositions of Gut Bacterial Populations and Bacteriophages in 5-11 Year-Olds Born Preterm Compared to Full Term.Frontiers in cellular and infection microbiology · 2020Article
- Association of Circulating Proinflammatory and Anti-inflammatory Protein Biomarkers in Extremely Preterm Born Children with Subsequent Brain Magnetic Resonance Imaging Volumes and Cognitive Function at Age 10 Years.The Journal of pediatrics · 2019Observational
- The emerging spectrum of early life exposure-related inflammation and epigenetic therapy.Cancer studies and molecular medicine : open journal · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
purpose of reviewSignificant research reveals that the microbiome modulates perinatal and postnatal health. This review aims to examine mechanisms by which intrauterine infection, the epigenome, and microbiome specifically influence preterm infant health outcomes. RECENT
findingsIntrauterine infection is a primary cause of preterm birth and can cause alterations in gene expression and epigenetic programming as well as postnatal inflammatory responses in the offspring. Insights from our own studies demonstrate epigenetic modifications of TLRs associated with exposure to intrauterine inflammation, as well as a cross talk between host epigenome and microbiome. Lastly, the gut microbiome modulates maturation of inflammatory pathways, which influences the development of preterm infants. SUMMARY: We present a unifying theme that preterm infant outcomes are associated with modulation of host immune and inflammatory responses, which are influenced by acute intrauterine infection, epigenetic, and microbiome factors.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.