Evidence map›Paper›PMID 29938126›Full record

ArticleJournal of pulmonary & respiratory medicine2017

Differential Effect of LPS on Glucose, Lactate and Inflammatory Markers in the Lungs of Normal and Diabetic Mice.

Cecilia Nagorny Holmberg, Annika Åstrand, Cecilia Wingren, James P Garnett, Gaëll Mayer, John D Taylor, Emma H Baker, Deborah L Baines

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in Journal of pulmonary & respiratory medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.1field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Cecilia Nagorny HolmbergRespiratory, Inflammation and Autoimmunity Innovative Medicines Research Unit, AstraZeneca Gothenburg, Pepparedsleden, Mölndal, Sweden.
Annika ÅstrandRespiratory, Inflammation and Autoimmunity Innovative Medicines Research Unit, AstraZeneca Gothenburg, Pepparedsleden, Mölndal, Sweden.
Cecilia WingrenRespiratory, Inflammation and Autoimmunity Innovative Medicines Research Unit, AstraZeneca Gothenburg, Pepparedsleden, Mölndal, Sweden.
James P GarnettInstitute for Infection and Immunity, St George's, University of London, London, UK.
Gaëll MayerRespiratory, Inflammation and Autoimmunity Innovative Medicines Research Unit, AstraZeneca Gothenburg, Pepparedsleden, Mölndal, Sweden.
John D TaylorRespiratory, Inflammation and Autoimmunity Innovative Medicines Research Unit, AstraZeneca Gothenburg, Pepparedsleden, Mölndal, Sweden.
Emma H BakerInstitute for Infection and Immunity, St George's, University of London, London, UK.
Deborah L BainesInstitute for Infection and Immunity, St George's, University of London, London, UK.
St George's, University of London · GB

Funding

Medical Research Council MR/K012770/1
6 · The paper itself

Abstract

Elevation of blood glucose results in increased glucose in the fluid that lines the surface of the airways and this is associated with an increased susceptibility to infection with respiratory pathogens. Infection induces an inflammatory response in the lung, but how this is altered by hyperglycemia and how this affects glucose, lactate and cytokine concentrations in the airway surface liquid is not understood. We used Wild Type (WT) and glucokinase heterozygote (GK

Indexed as

AirwayGlucoseHyperglycemiaInflammationMetabolism

Identifiers

PMID29938126
PMCPMC6010169
OpenAlexW2988968723

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.