Evidence map›Paper›PMID 29938000›Full record

ArticleOncotarget2018

Anti-cancer binary system activated by bacteriophage HK022 integrase.

Amer Elias, Natasha Gritsenko, Rena Gorovits, Itay Spector, Gali Prag, Ezra Yagil, Mikhail Kolot

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Amer EliasDepartment of Biochemistry and Molecular Biology, Tel-Aviv University, Tel-Aviv 69978, Israel.
Natasha GritsenkoDepartment of Biochemistry and Molecular Biology, Tel-Aviv University, Tel-Aviv 69978, Israel.
Rena GorovitsInstitute of Plant Sciences and Genetics in Agriculture, Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, Rehovot 76100, Israel.
Itay SpectorDepartment of Biochemistry and Molecular Biology, Tel-Aviv University, Tel-Aviv 69978, Israel.
Gali PragDepartment of Biochemistry and Molecular Biology, Tel-Aviv University, Tel-Aviv 69978, Israel.
Ezra YagilDepartment of Biochemistry and Molecular Biology, Tel-Aviv University, Tel-Aviv 69978, Israel.
Mikhail KolotDepartment of Biochemistry and Molecular Biology, Tel-Aviv University, Tel-Aviv 69978, Israel.
Tel Aviv University · ILHebrew University of Jerusalem · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The binary system presented in this work is based on the bacteriophage HK022 integrase recombinase that activates the expression of a silenced Diphtheria toxin gene, both controlled by the cancer specific

Indexed as

cancer therapycoliphage HK022 integraseDTA toxinlung cancersite-specific recombination

Identifiers

PMID29938000
PMCPMC6007955
OpenAlexW2952174607

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.