Evidence map›Paper›PMID 29937986›Full record

ArticleJournal of radiation oncology2018

Effect of BioZorb® surgical marker placement on post-operative radiation boost target volume.

Naomi Wiens, Lisa Torp, Brynn Wolff, Yijin Wert, Katherine Barton, David Weksberg, Joella Wilson-Dagar

Open access · hybridAbstract read
In one paragraph

Article in Journal of radiation oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Naomi WiensUPMC Pinnacle Cancer Institute, 4300 Londonderry Road, Harrisburg, PA 17109 USA.
Lisa TorpUPMC Pinnacle Cancer Institute, 4300 Londonderry Road, Harrisburg, PA 17109 USA.
Brynn WolffUPMC Pinnacle Cancer Institute, 4300 Londonderry Road, Harrisburg, PA 17109 USA.
Yijin WertUPMC Pinnacle Cancer Institute, 4300 Londonderry Road, Harrisburg, PA 17109 USA.
Katherine BartonUPMC Pinnacle Cancer Institute, 4300 Londonderry Road, Harrisburg, PA 17109 USA.
David WeksbergUPMC Pinnacle Cancer Institute, 4300 Londonderry Road, Harrisburg, PA 17109 USA.
Joella Wilson-DagarUPMC Pinnacle Cancer Institute, 4300 Londonderry Road, Harrisburg, PA 17109 USA.
UPMC Central Pa · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveBioZorb® is a tumor bed marker placed during partial mastectomy for targeted post-operative radiation. This study was designed to evaluate BioZorb® effect on radiation boost clinical target volume (CTV), planning target volume (PTV), median dose to ipsilateral lung (Gy), and heart irradiation in left-sided cancers.

methodsData was collected via a retrospective cohort study with two study arms: BioZorb® intra-operative placement versus no BioZorb® placement. Patients were stratified by BMI, age, tumor laterality and volume, and cancer stage. Mean, standard deviation, median, range of cubic centimeters of clinical and planning target volume, cardiac dose in left-sided cancers, ipsilateral lung dose, and volume of ipsilateral lung receiving 20 Gy were reported.

resultsOf 143 patients, median CTV (cm

conclusionThe BioZorb® arm showed statistically significant reductions in CTV and PTV but not ipsilateral lung or heart irradiation.

Indexed as

Bioabsorbable surgical markerBoost radiationBreast-conserving therapyOncoplasticRadiation reduction

Identifiers

PMID29937986
PMCPMC5978798
OpenAlexW2781847168

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.