ArticleJournal of research in medical sciences : the official journal of Isfahan University of Medical Sciences2018
Serum procollagen type 1 N propeptide: A novel diagnostic test for diabetic foot osteomyelitis - A case-control study.
Article in Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.
What it found
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The trial behind it
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Who cites it
4 citing papers in PubMed, 2 syntheses or guidelines pooled it, 7 citations in OpenAlex.
- Is procalcitonin superior to CRP and ESR in the diagnosis of diabetic foot osteomyelitis? A systematic review and meta-analysis.BMC infectious diseases · 2026Pooled it
- Pooled it
- Biochemical markers of bone metabolism and bone mineral density in patients with type 2 diabetic foot ulcer.BMC endocrine disorders · 2026Article
- The infected diabetic foot: Modulation of traditional biomarkers for osteomyelitis diagnosis in the setting of diabetic foot infection and renal impairment.International wound journal · 2024Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe objective of the study was to determine whether serum levels of procollagen type 1 MATERIALS AND
methodsA case-control study was designed comparing the aforementioned groups. Patients were classified as osteomyelitis and controls based on the International Working Group diagnostic criteria. Serum P1NP and three other inflammatory markers, namely, C-reactive protein (CRP), white blood cells (WBC), and platelets were analyzed on patients with DFO and controls.
resultsThe mean serum P1NP levels were significantly higher in the DFO group (
conclusionWe found marked elevation of serum P1NP in diabetic foot ulcer with bone infection with potential value in using it to diagnose DFO.
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Registered trials
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