ArticleIndian journal of dermatology
Serum Zinc Level in Vitiligo: A Case-control Study.
Article in Indian journal of dermatology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.
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Who cites it
10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 30 citations in OpenAlex.
- Zinc, copper, and selenium levels in vitiligo: a systematic review and meta-analysis.Scientific reports · 2024Pooled it
- Healthy lifestyle choices: new insights into vitiligo management.Frontiers in immunology · 2024Pooled it
- Regulatory Effects of Thai Rice By-Product Extracts fromPlants (Basel, Switzerland) · 2023Article
- Possible relationship between poor skin disorders prognosis and serum zinc level: A narrative review.Dermatology reports · 2022Article
- Article
- Serum Copper and Zinc Levels Among Iranian Vitiligo Patients.Dermatology practical & conceptual · 2022Article
- Trace element zinc and skin disorders.Frontiers in medicine · 2022Review
- Are Patients with Vitiligo More Prone to Myocardial Infarction?: A Case-control Study.The Journal of clinical and aesthetic dermatology · 2019Article
- Cultured Epidermal Melanocyte Transplantation in Vitiligo: A Review Article.Iranian journal of public health · 2019Review
- Hearing status in patients with vitiligo.Clinical, cosmetic and investigational dermatology · 2019Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundVitiligo is characterized by the idiopathic destruction of melanocytes, probably of autoimmune etiology, that results in depigmented patches of skin and mucosal surfaces. Oxidative stress may contribute to the pathogenesis of vitiligo. Zinc, a trace element with antiapoptotic properties, plays a major role in the process of melanogenesis and elimination of free radicals. The present study was conducted with the aim of comparing serum zinc levels in patients with vitiligo and in normal controls. MATERIALS AND
methodsIn this case-control study, we studied 103 patients with vitiligo and 103 healthy sex-and age-matched controls. Serum zinc levels were measured in these two groups using atomic absorption spectrophotometry and compared with each other.
resultsThe mean serum zinc level was 92.1 mcg/dl in the focal vitiligo, 81.3 mcg/dl in the generalized vitiligo, and 91.8 mcg/dl in the control group. A significant difference in serum zinc levels was observed between the patients with generalized vitiligo and the controls. Lower serum zinc levels were also correlated with longer duration of the disease. Furthermore, a negative relationship was found between serum zinc level and age of patients with vitiligo.
conclusionSerum zinc level is low in patients with generalized vitiligo. In these patients, serum zinc level is in negative correlation with patient's age and disease duration.
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