Evidence map›Paper›PMID 29937407›Full record

ArticleCell chemical biology2018

Genetically Encoded Protein Phosphorylation in Mammalian Cells.

Václav Beránek, Christopher D Reinkemeier, Michael S Zhang, Alexandria D Liang, Gene Kym, Jason W Chin

Open access · hybridAbstract read
In one paragraph

Article in Cell chemical biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 69 citations in OpenAlex.

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  4. Human Synthetic Biology and Programmable Gene Regulation Control.Annual review of genomics and human genetics · 2025
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  15. Chemical proteomics approaches for protein post-translational modification studies.Biochimica et biophysica acta. Proteins and proteomics · 2024
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Václav BeránekMedical Research Council Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge, UK.
Christopher D ReinkemeierMedical Research Council Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge, UK.
Michael S ZhangMedical Research Council Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge, UK.
Alexandria D LiangMedical Research Council Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge, UK.
Gene KymMedical Research Council Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge, UK.
Jason W ChinMedical Research Council Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge, UK. Electronic address: chin@mrc-lmb.cam.ac.uk.
Medical Research Council · GBMRC Laboratory of Molecular Biology · GB

Funding

Medical Research Council MC_U105181009Medical Research Council MC_UP_A024_1008
6 · The paper itself

Abstract

Protein phosphorylation regulates diverse processes in eukaryotic cells. Strategies for installing site-specific phosphorylation in target proteins in eukaryotic cells, through routes that are orthogonal to enzymatic post-translational modification, would provide a powerful route for defining the consequences of particular phosphorylations. Here we show that the SepRS

Indexed as

Genetic CodeAmino Acyl-tRNA SynthetasesAnimalsBiosynthetic PathwaysCrystallography, X-RayHEK293 CellsHumansMethanococcusOrganophosphonatesPeptide Elongation Factor 1PhosphorylationPhosphoserineProtein EngineeringProteinsAmino Acyl-tRNA SynthetasesOrganophosphonatesPeptide Elongation Factor 1PhosphoserineProteinsgenetic code expansionmammalian cellsphosphorylationphosphoserinephosphoserine analogsynthetic biology

Identifiers

PMID29937407
PMCPMC6162345
OpenAlexW2808770696

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.