Evidence map›Paper›PMID 29937277›Full record

ArticleNeuron2018

Vascular Compartmentalization of Functional Hyperemia from the Synapse to the Pia.

Ravi L Rungta, Emmanuelle Chaigneau, Bruno-Félix Osmanski, Serge Charpak

Erratum issuedOpen access · bronzeAbstract read
In one paragraph

Article in Neuron, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 168 papers.

0numbers the graph read from it
0cells of the map it votes in
168citing papers in PubMed
12.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

168 citing papers in PubMed, 252 citations in OpenAlex.

  1. Article
  2. Ultrafast venous and sagittal sinus constrictions in the brain driven by abdominal pressure.Proceedings of the National Academy of Sciences of the United States of America · 2026
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  3. Review
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  6. A pericyte chloride clamp mechanism governs capillary control of cerebral blood flow.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  7. Cerebral capillary computation.American journal of physiology. Cell physiology · 2026
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. TMagnetic resonance in medicine · 2026
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Eppur si muove: the dynamic brain pericyte.Fluids and barriers of the CNS · 2025
    Review
  19. Systemic nimodipine affects pericyte calcium signaling, resting hemodynamics and neurovascular coupling in healthy mouse brain.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025
    Article
  20. Cerebral blood flow is modulated by astrocytic cAMP elevation independently of IPProceedings of the National Academy of Sciences of the United States of America · 2025
    Article

108 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Ravi L RungtaINSERM U1128, Laboratory of Neurophysiology and New Microscopy, Université Paris Descartes, Paris 75006, France. Electronic address: ravi.rungta@parisdescartes.fr.
Emmanuelle ChaigneauINSERM U1128, Laboratory of Neurophysiology and New Microscopy, Université Paris Descartes, Paris 75006, France.
Bruno-Félix OsmanskiINSERM U1128, Laboratory of Neurophysiology and New Microscopy, Université Paris Descartes, Paris 75006, France.
Serge CharpakINSERM U1128, Laboratory of Neurophysiology and New Microscopy, Université Paris Descartes, Paris 75006, France. Electronic address: serge.charpak@parisdescartes.fr.
Université Paris Cité · FRInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Functional hyperemia, a regional increase of blood flow triggered by local neural activation, is used to map brain activity in health and disease. However, the spatial-temporal dynamics of functional hyperemia remain unclear. Two-photon imaging of the entire vascular arbor in NG2-creERT2;GCaMP6f mice shows that local synaptic activation, measured via oligodendrocyte precursor cell (OPC) Ca

Indexed as

AnimalsBrainBrain ChemistryHyperemiaMiceMice, Inbred C57BLMice, TransgenicMicroscopy, ConfocalMuscle, Smooth, VascularPericytesPia MaterSynapsesanesthetizedastrocyteawakeblood-brain barriercalciumCBFendotheliumfunctional imaginggap junctiongliaglutamatehyperpolarizationin vivomicrovascularneuronneurovascular couplingneurovascular unitodor

Identifiers

PMID29937277
PMCPMC6069674
OpenAlexW2809129903

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.