ReviewMolecular diversity2018
Current progress in asymmetric Biginelli reaction: an update.
Review in Molecular diversity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed.
- Defect-rich MOF-303 as a dual acid-base heterogeneous catalyst for the one-pot Biginelli synthesis of dihydropyrimidinones.Scientific reports · 2025Article
- Precision in stereochemistry: the integral role of catalytic asymmetric Biginelli reaction in crafting enantiomerically pure dihydropyrimidinones.Molecular diversity · 2024Review
- Diverse Methods with Stereoselective Induction in the Asymmetric Biginelli Reaction.Molecules (Basel, Switzerland) · 2024Review
- Synthesis of 3,4-Dihydropyrimidin(thio)one Containing Scaffold: Biginelli-like Reactions.Pharmaceuticals (Basel, Switzerland) · 2022Review
- Synthesis and Characterization of Dihydrouracil Analogs Utilizing Biginelli Hybrids.Molecules (Basel, Switzerland) · 2022Article
- Biginelli Reaction Mediated Synthesis of Antimicrobial Pyrimidine Derivatives and Their Therapeutic Properties.Molecules (Basel, Switzerland) · 2021Review
- Overview on magnetically recyclable ferrite nanoparticles: synthesis and their applications in coupling and multicomponent reactions.RSC advances · 2021Review
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Biginelli reaction, involving a three-component reaction of an aromatic aldehyde, urea and ethyl acetoacetate, has emerged as an extremely useful synthetic tool to organic chemists for the synthesis of 3,4-dihydropyrimidine-2-(1H)-ones and related heterocyclic compounds. In the past decades, the asymmetric variants of this reaction have been at the forefront of investigations in several research groups. In 2013, we highlighted the developments occurred in the asymmetric version of the Biginelli reaction. This review article focuses on the recent developments of asymmetric Biginelli reaction covers the literature going back to 2012.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.