Evidence map›Paper›PMID 29936623›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2019

Handgrip fatiguing exercise can provide objective assessment of cancer-related fatigue: a pilot study.

T Veni, S Boyas, B Beaune, H Bourgeois, A Rahmani, S Landry, A Bochereau, S Durand, B Morel

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In one paragraph

Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.2field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 37 citations in OpenAlex.

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  6. Objective measurement of cancer-related fatigue.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Review
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  9. Observational
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  13. Physiological and psychosocial correlates of cancer-related fatigue.Journal of cancer survivorship : research and practice · 2022
    Article
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  15. Cancer-related fatigue and its determinants in a cohort of women with breast cancer: the DAMA Cohort.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

T VeniLaboratoire Motricité, Interactions, Performance, MIP - EA4334, Le Mans Université, Avenue Olivier Messiaen, 72085, Le Mans Cedex 9, France.
S BoyasLaboratoire Motricité, Interactions, Performance, MIP - EA4334, Le Mans Université, Avenue Olivier Messiaen, 72085, Le Mans Cedex 9, France.
B BeauneLaboratoire Motricité, Interactions, Performance, MIP - EA4334, Le Mans Université, Avenue Olivier Messiaen, 72085, Le Mans Cedex 9, France.
H BourgeoisInter-regional Institute of Cancerology Jean Bernard, Le Mans, France.
A RahmaniLaboratoire Motricité, Interactions, Performance, MIP - EA4334, Le Mans Université, Avenue Olivier Messiaen, 72085, Le Mans Cedex 9, France.
S LandryInter-regional Institute of Cancerology Jean Bernard, Le Mans, France.
A BochereauLaboratoire Motricité, Interactions, Performance, MIP - EA4334, Le Mans Université, Avenue Olivier Messiaen, 72085, Le Mans Cedex 9, France.
S DurandLaboratoire Motricité, Interactions, Performance, MIP - EA4334, Le Mans Université, Avenue Olivier Messiaen, 72085, Le Mans Cedex 9, France.
B MorelLaboratoire Motricité, Interactions, Performance, MIP - EA4334, Le Mans Université, Avenue Olivier Messiaen, 72085, Le Mans Cedex 9, France. baptiste.morel-prieur@univ-lemans.fr.ORCID http://orcid.org/0000-0002-2872-6423
Le Mans Université · FRCentre Jean Bernard · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAs a subjective symptom, cancer-related fatigue is assessed via patient-reported outcomes. Due to the inherent bias of such evaluation, screening and treatment for cancer-related fatigue remains suboptimal. The purpose is to evaluate whether objective cancer patients' hand muscle mechanical parameters (maximal force, critical force, force variability) extracted from a fatiguing handgrip exercise may be correlated to the different dimensions (physical, emotional, and cognitive) of cancer-related fatigue.

methodsFourteen women with advanced breast cancer, still under or having previously received chemotherapy within the preceding 3 months, and 11 healthy women participated to the present study. Cancer-related fatigue was first assessed through the EORTC QLQ-30 and its fatigue module. Fatigability was then measured during 60 maximal repeated handgrip contractions. The maximum force, critical force (asymptote of the force-time evolution), and force variability (root mean square of the successive differences) were extracted. Multiple regression models were performed to investigate the influence of the force parameters on cancer-related fatigue's dimensions.

resultsThe multiple linear regression analysis evidenced that physical fatigue was best explained by maximum force and critical force (r = 0.81; p = 0.029). The emotional fatigue was best explained by maximum force, critical force, and force variability (r = 0.83; p = 0.008). The cognitive fatigue was best explained by critical force and force variability (r = 0.62; p = 0.035).

conclusionThe handgrip maximal force, critical force, and force variability may offer objective measures of the different dimensions of cancer-related fatigue and could provide a complementary approach to the patient reported outcomes.

Indexed as

Activities of Daily LivingAdultBreast NeoplasmsCase-Control StudiesExerciseFatigueFemaleHand StrengthHumansLeisure ActivitiesMiddle AgedMuscle FatigueMuscle, SkeletalPilot ProjectsQuality of LifeSurveys and QuestionnairesBreast cancerForceNeuromuscular fatiguePhysical activityQuality of life

Identifiers

PMID29936623
OpenAlexW2810947713

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.