Evidence map›Paper›PMID 29936622›Full record

ArticleParasitology research2018

Higher vaginal pH in Trichomonas vaginalis infection with intermediate Nugent score in reproductive-age women-a hospital-based cross-sectional study in Odisha, India.

Padmalaya Das, Tapoja Swain, Jyoti Ranjan Mohanty, Shalini Sinha, Bijay Padhi, Belen Torondel, Oliver Cumming, Bijaya Panda, Arati Nayak, Pinaki Panigrahi

Abstract read
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In one paragraph

Article in Parasitology research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Concordance Between Clinical and Laboratory Diagnosis of Abnormal Vaginal Discharge in Chilean Women.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2021
    Article
  4. Factors associated with Trichomonas vaginalis infection in reproductive-aged women attending cervical screening in southeast of Brazil.The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Padmalaya DasInfection Biology Program, School of Life Sciences, AIPH University, Bhubaneswar, Odisha, India.
Tapoja SwainInfection Biology Program, School of Life Sciences, AIPH University, Bhubaneswar, Odisha, India.
Jyoti Ranjan MohantyInfection Biology Program, School of Life Sciences, AIPH University, Bhubaneswar, Odisha, India.
Shalini SinhaInfection Biology Program, School of Life Sciences, AIPH University, Bhubaneswar, Odisha, India.
Bijay PadhiInfection Biology Program, School of Life Sciences, AIPH University, Bhubaneswar, Odisha, India.
Belen TorondelDepartment of Disease Control, London School of Hygiene and Tropical Medicine, London, UK.
Oliver CummingDepartment of Disease Control, London School of Hygiene and Tropical Medicine, London, UK.
Bijaya PandaDepartment of Obstetrics and Gynecology, Capital Hospital, Bhubaneswar, Odisha, India.
Arati NayakDepartment of Obstetrics and Gynecology, Capital Hospital, Bhubaneswar, Odisha, India.
Pinaki PanigrahiDepartments of Epidemiology and Pediatrics, Center for Global Health and Development, College of Public Health, University of Nebraska Medical Center, Omaha, NE, USA. ppanigrahi@unmc.edu.
Asian Institute of Public Health · INLondon School of Hygiene & Tropical Medicine · GBCenter for Global Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A close association between Trichomonas vaginalis (TV) infection and bacterial vaginosis (BV) has been reported. Some other studies have found association is stronger with intermediate Nugent score than BV. Most studies have used wet mount microscopy, a relatively insensitive method, to detect TV infection. We wanted to study the association of TV infection with BV and with intermediate Nugent score. We undertook a cross-sectional hospital-based study of 1110 non-pregnant women from Odisha state, India, aged between 18 and 45 years, collecting vaginal swabs for diagnosis of BV by Nugent score (NS) criteria and TV by PCR analysis. TV infection was found in 13.3% of women with intermediate Nugent score (NS 4-6) and 13.6% with BV (NS 7-10). Before adjustment, TV infection was associated with BV, intermediate Nugent, vaginal pH ≥ 4.5, and age group between 26 and 35 years. Multivariate analysis confirmed that TV infection was more likely to have raised vaginal pH, either BV or intermediate Nugent. Proportion of TV cases increased sequentially with the increase in Nugent score up to NS 6, after which a decline was observed. Vaginal pH was higher in the TV-infected group than the uninfected group in women with intermediate Nugent, but no difference was noticed in women with BV. TV infection was equally prevalent in women with intermediate Nugent as well as BV. In the intermediate Nugent group women, TV infection was found only when vaginal pH was raised, indicating a crucial role of vaginal pH in determining TV infection.

Indexed as

AdolescentAdultCross-Sectional StudiesFemaleHumansHydrogen-Ion ConcentrationIndiaMiddle AgedPrevalenceTrichomonas vaginalisTrichomonas VaginitisVaginaYoung AdultBacterial vaginosisNon-pregnant womanNugent scoreTrichomonas vaginalisVaginal pH

Identifiers

PMID29936622
OpenAlexW2811182439

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.