Evidence map›Paper›PMID 29936600›Full record

Trial reportJournal of anesthesia2018

Effects of epidural anesthesia on postoperative nausea and vomiting in laparoscopic gynecological surgery: a randomized controlled trial.

Hiroyuki Seki, Kyoko Furumoto, Masato Sato, Aya Kagoya, Hiroka Hashimoto, Yoshihiro Sekiguchi, Itsuo Nakatsuka

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Journal of anesthesia, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Trial
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Hiroyuki SekiDepartment of Anesthesiology, Tokyo Saiseikai Central Hospital, 4-17 Mita 1-chome, Minato-ku, Tokyo, 108-0073, Japan. hseki.a3@keio.jp.
Kyoko FurumotoDepartment of Anesthesiology, Tokyo Saiseikai Central Hospital, 4-17 Mita 1-chome, Minato-ku, Tokyo, 108-0073, Japan.
Masato SatoDepartment of Anesthesiology, Keiyu Hospital, Yokohama, Kanagawa, Japan.
Aya KagoyaDepartment of Anesthesiology, Tokyo Saiseikai Central Hospital, 4-17 Mita 1-chome, Minato-ku, Tokyo, 108-0073, Japan.
Hiroka HashimotoDepartment of Anesthesiology, Tokyo Saiseikai Central Hospital, 4-17 Mita 1-chome, Minato-ku, Tokyo, 108-0073, Japan.
Yoshihiro SekiguchiDepartment of Anesthesiology, Tokyo Saiseikai Central Hospital, 4-17 Mita 1-chome, Minato-ku, Tokyo, 108-0073, Japan.
Itsuo NakatsukaDepartment of Anesthesiology, Tokyo Saiseikai Central Hospital, 4-17 Mita 1-chome, Minato-ku, Tokyo, 108-0073, Japan.
Saiseikai Central Hospital · JPkeiyu Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePatients undergoing laparoscopic gynecological surgery are susceptible to postoperative nausea and vomiting (PONV). We hypothesized that a combination of epidural and general anesthesia to minimize intraoperative opioid administration would reduce the incidence of PONV following laparoscopic gynecological surgery.

methodsWomen undergoing elective laparoscopic gynecological surgery were randomly assigned to receive general anesthesia alone (group G, n = 45) or general anesthesia with epidural anesthesia (group GE, n = 45). Patients in group G received fentanyl and remifentanil for intraoperative analgesia, and those in group GE received single-shot ropivacaine at the time of induction of anesthesia. The primary outcome was the incidence of PONV within 24 h of surgery. Secondary outcomes included the use of rescue metoclopramide within 24 h of surgery and the time to first incidence of PONV and first use of rescue metoclopramide.

resultsThe incidence of PONV within 24 h of surgery was 60.0% in group G and 44.4% in group GE [relative risk (RR): 0.53, 95% confidence interval (CI): 0.23-1.23, p = 0.14]. There were no intergroup differences in the use of rescue metoclopramide (40.0% in group G, 24.4% in group GE, RR: 0.49, 95% CI 0.20-1.20, p = 0.11) and the time to first incidence of PONV and first use of rescue metoclopramide (p = 0.20 and 0.12, respectively).

conclusionMinimizing intraoperative opioid administration by combining epidural and general anesthesia did not reduce the 24-h incidence of PONV or rescue metoclopramide use after laparoscopic gynecological surgery.

Indexed as

AdultAnalgesics, OpioidAnesthesia, EpiduralAnesthesia, GeneralAntiemeticsFemaleFentanylGynecologic Surgical ProceduresHumansLaparoscopyMetoclopramideMiddle AgedPainPostoperative Nausea and VomitingRemifentanilAnalgesics, OpioidAntiemeticsFentanylMetoclopramideRemifentanilEpidural anesthesiaGynecological surgeryLaparoscopic surgeryPostoperative nausea and vomiting

Identifiers

PMID29936600
OpenAlexW2809952765

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.