Evidence map›Paper›PMID 29936585›Full record

ArticleNaunyn-Schmiedeberg's archives of pharmacology2018

Antioxidant resveratrol protects against copper oxide nanoparticle toxicity in vivo.

Sana Khalid, Nabeel Afzal, Junaid Ali Khan, Zulfia Hussain, Anas Sarwar Qureshi, Hafeez Anwar, Yasir Jamil

Abstract read
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In one paragraph

Article in Naunyn-Schmiedeberg's archives of pharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Copper Homeostasis and Cuproptosis in Neurological Disorders.Drug design, development and therapy · 2026
    Review
  3. Copper Toxicity in Animals: A Review.Biological trace element research · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Sana KhalidInstitute of Pharmacy, Physiology and Pharmacology, University of Agriculture, Faisalabad, 38040, Pakistan.
Nabeel AfzalInstitute of Pharmacy, Physiology and Pharmacology, University of Agriculture, Faisalabad, 38040, Pakistan.
Junaid Ali KhanInstitute of Pharmacy, Physiology and Pharmacology, University of Agriculture, Faisalabad, 38040, Pakistan. Junaidali.khan@uaf.edu.pk.ORCID 0000-0003-2630-1744
Zulfia HussainInstitute of Pharmacy, Physiology and Pharmacology, University of Agriculture, Faisalabad, 38040, Pakistan.
Anas Sarwar QureshiDepartment of Anatomy, University of Agriculture, Faisalabad, 38040, Pakistan.
Hafeez AnwarDepartment of Physics, University of Agriculture, Faisalabad, 38040, Pakistan.
Yasir JamilDepartment of Physics, University of Agriculture, Faisalabad, 38040, Pakistan.
University of Agriculture Faisalabad · PK

Funding

Higher Education Commission, Pakistan 213-58222-2BM2-162Higher Education Commission, Pakistan 6380/Punjab/NRPU/R&D/HEC/2016
6 · The paper itself

Abstract

The upsurge in copper oxide nanoparticle (CuONP) applications in various fields triggers hazardous effects on health. Resveratrol, a polyphenol found in plants of stilbene class, has been reported to decrease oxidative stress. The current study investigated the protective effect of resveratrol (RVT) against CuONP-induced hepatotoxicity and nephrotoxicity in male Wistar rats. CuONPs were prepared by precipitation method and characterized by X-ray diffraction (XRD) technique and scanning electron microscopy (SEM). Average crystallite size, lattice parameters (a, b, and c), volume of unit cell, and X-ray density were found to be 33 nm, (a = 4.691 Å, b = 3.409 Å, and c = 5.034 Å), 79.4 Å

Indexed as

AnimalsAntioxidantsCopperCreatinineKidneyMaleNanoparticlesOxidative StressRats, WistarResveratrolUreaAntioxidantsCopperCreatininecuprous oxideResveratrolUreaCopper oxide nanoparticlesHepatotoxicityHistopathologyNephrotoxicityOxidative stressResveratrol

Identifiers

PMID29936585
OpenAlexW2810819723

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.